Wefers B - Search Results

1

Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.

Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: wefers b. Immunity. 2024 Nov 12;57(11):2651-2668.e12. doi: 10.1016/j.immuni.2024.09.014. Epub 2024 Oct 16. Immunity. 2024. PMID: 39419029 Free article.

2

Editing and investigating genomes with TALE and CRISPR/Cas systems: genome engineering across species using TALENs.

Kühn R, Wefers B. Kühn R, et al. Among authors: wefers b. Methods. 2014 Aug 15;69(1):1. doi: 10.1016/j.ymeth.2014.08.012. Methods. 2014. PMID: 25194988 No abstract available.

3

Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference.

Di Benedetto B, Wefers B, Wurst W, Kühn R. Di Benedetto B, et al. Among authors: wefers b. Mol Biotechnol. 2009 Mar;41(3):263-9. doi: 10.1007/s12033-008-9125-9. Epub 2008 Dec 4. Mol Biotechnol. 2009. PMID: 19052925 Free PMC article.

4

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.

Wefers B, Meyer M, Ortiz O, Hrabé de Angelis M, Hansen J, Wurst W, Kühn R. Wefers B, et al. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3782-7. doi: 10.1073/pnas.1218721110. Epub 2013 Feb 20. Proc Natl Acad Sci U S A. 2013. PMID: 23426636 Free PMC article.

5

Highly efficient targeted mutagenesis in mice using TALENs.

Panda SK, Wefers B, Ortiz O, Floss T, Schmid B, Haass C, Wurst W, Kühn R. Panda SK, et al. Among authors: wefers b. Genetics. 2013 Nov;195(3):703-13. doi: 10.1534/genetics.113.156570. Epub 2013 Aug 26. Genetics. 2013. PMID: 23979585 Free PMC article.

6

Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.

Wefers B, Panda SK, Ortiz O, Brandl C, Hensler S, Hansen J, Wurst W, Kühn R. Wefers B, et al. Nat Protoc. 2013 Dec;8(12):2355-79. doi: 10.1038/nprot.2013.142. Epub 2013 Oct 31. Nat Protoc. 2013. PMID: 24177293

7

Generation of targeted mouse mutants by embryo microinjection of TALENs.

Wefers B, Ortiz O, Wurst W, Kühn R. Wefers B, et al. Methods. 2014 Aug 15;69(1):94-101. doi: 10.1016/j.ymeth.2014.01.002. Epub 2014 Jan 11. Methods. 2014. PMID: 24418396

8

Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.

Brandl C, Ortiz O, Röttig B, Wefers B, Wurst W, Kühn R. Brandl C, et al. Among authors: wefers b. FEBS Open Bio. 2014 Dec 3;5:26-35. doi: 10.1016/j.fob.2014.11.009. eCollection 2015. FEBS Open Bio. 2014. PMID: 25685662 Free PMC article.

9

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

Chu VT, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, Kühn R. Chu VT, et al. Among authors: wefers b. Nat Biotechnol. 2015 May;33(5):543-8. doi: 10.1038/nbt.3198. Epub 2015 Mar 24. Nat Biotechnol. 2015. PMID: 25803306

10

Design and Generation of Gene-Targeting Vectors.

Wefers B, Wurst W, Kühn R. Wefers B, et al. Curr Protoc Mouse Biol. 2011 Mar 1;1(1):199-211. doi: 10.1002/9780470942390.mo100179. Curr Protoc Mouse Biol. 2011. PMID: 26068993

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