Willem M - Search Results

1

Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.

Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: willem m. Immunity. 2024 Nov 12;57(11):2651-2668.e12. doi: 10.1016/j.immuni.2024.09.014. Epub 2024 Oct 16. Immunity. 2024. PMID: 39419029 Free article.

2

Lack of β-amyloid cleaving enzyme-1 (BACE1) impairs long-term synaptic plasticity but enhances granule cell excitability and oscillatory activity in the dentate gyrus in vivo.

Vnencak M, Schölvinck ML, Schwarzacher SW, Deller T, Willem M, Jedlicka P. Vnencak M, et al. Among authors: willem m. Brain Struct Funct. 2019 Apr;224(3):1279-1290. doi: 10.1007/s00429-019-01836-6. Epub 2019 Jan 30. Brain Struct Funct. 2019. PMID: 30701309

3

Basement membrane-dependent survival of retinal ganglion cells.

Halfter W, Willem M, Mayer U. Halfter W, et al. Among authors: willem m. Invest Ophthalmol Vis Sci. 2005 Mar;46(3):1000-9. doi: 10.1167/iovs.04-1185. Invest Ophthalmol Vis Sci. 2005. PMID: 15728558

4

Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD).

Edbauer D, Willem M, Lammich S, Steiner H, Haass C. Edbauer D, et al. Among authors: willem m. J Biol Chem. 2002 Apr 19;277(16):13389-93. doi: 10.1074/jbc.M111571200. Epub 2002 Jan 23. J Biol Chem. 2002. PMID: 11809755 Free article.

5

Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface.

Kaether C, Schmitt S, Willem M, Haass C. Kaether C, et al. Among authors: willem m. Traffic. 2006 Apr;7(4):408-15. doi: 10.1111/j.1600-0854.2006.00396.x. Traffic. 2006. PMID: 16536739 Free article.

6

Function, regulation and therapeutic properties of beta-secretase (BACE1).

Willem M, Lammich S, Haass C. Willem M, et al. Semin Cell Dev Biol. 2009 Apr;20(2):175-82. doi: 10.1016/j.semcdb.2009.01.003. Epub 2009 Jan 20. Semin Cell Dev Biol. 2009. PMID: 19429494 Review.

7

BACE1 Dependent Neuregulin Proteolysis.

Fleck D, Garratt AN, Haass C, Willem M. Fleck D, et al. Among authors: willem m. Curr Alzheimer Res. 2011 May 23. Online ahead of print. Curr Alzheimer Res. 2011. PMID: 21605034

8

Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.

Velanac V, Unterbarnscheidt T, Hinrichs W, Gummert MN, Fischer TM, Rossner MJ, Trimarco A, Brivio V, Taveggia C, Willem M, Haass C, Möbius W, Nave KA, Schwab MH. Velanac V, et al. Among authors: willem m. Glia. 2012 Feb;60(2):203-17. doi: 10.1002/glia.21255. Epub 2011 Nov 2. Glia. 2012. PMID: 22052506 Free PMC article.

9

Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.

Lammich S, Kamp F, Wagner J, Nuscher B, Zilow S, Ludwig AK, Willem M, Haass C. Lammich S, et al. Among authors: willem m. J Biol Chem. 2011 Dec 30;286(52):45063-72. doi: 10.1074/jbc.M111.296921. Epub 2011 Nov 7. J Biol Chem. 2011. PMID: 22065584 Free PMC article.

10

BACE1 dependent neuregulin processing: review.

Fleck D, Garratt AN, Haass C, Willem M. Fleck D, et al. Among authors: willem m. Curr Alzheimer Res. 2012 Feb;9(2):178-83. doi: 10.2174/156720512799361637. Curr Alzheimer Res. 2012. PMID: 22455478 Review.

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