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MHConstructor: A high-throughput, haplotype-informed solution to the MHC assembly challenge.
Wade KJ, Suseno R, Kizer K, Williams J, Boquett J, Caillier S, Pollock NR, Renschen A, Santaniello A, Oksenberg JR, Norman PJ, Augusto DG, Hollenbach JA. Wade KJ, et al. Among authors: santaniello a. bioRxiv [Preprint]. 2024 May 21:2024.05.20.595060. doi: 10.1101/2024.05.20.595060. bioRxiv. 2024. Update in: Genome Biol. 2024 Oct 17;25(1):274. doi: 10.1186/s13059-024-03412-6 PMID: 38826378 Free PMC article. Updated. Preprint.
Next-generation sequencing reveals new information about HLA allele and haplotype diversity in a large European American population.
Creary LE, Gangavarapu S, Mallempati KC, Montero-Martín G, Caillier SJ, Santaniello A, Hollenbach JA, Oksenberg JR, Fernández-Viña MA. Creary LE, et al. Among authors: santaniello a. Hum Immunol. 2019 Oct;80(10):807-822. doi: 10.1016/j.humimm.2019.07.275. Epub 2019 Jul 22. Hum Immunol. 2019. PMID: 31345698 Free PMC article.
High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility.
Osoegawa K, Creary LE, Montero-Martín G, Mallempati KC, Gangavarapu S, Caillier SJ, Santaniello A, Isobe N, Hollenbach JA, Hauser SL, Oksenberg JR, Fernández-Viňa MA. Osoegawa K, et al. Among authors: santaniello a. Front Immunol. 2021 May 25;12:644838. doi: 10.3389/fimmu.2021.644838. eCollection 2021. Front Immunol. 2021. PMID: 34211458 Free PMC article. Clinical Trial.
A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease.
Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, Hauser SL, Fernandez-Viña M, Oksenberg JR. Hollenbach JA, et al. Among authors: santaniello a. Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7419-7424. doi: 10.1073/pnas.1821778116. Epub 2019 Mar 25. Proc Natl Acad Sci U S A. 2019. PMID: 30910980 Free PMC article. Clinical Trial.
Mitochondrial DNA sequence variation in multiple sclerosis.
Tranah GJ, Santaniello A, Caillier SJ, D'Alfonso S, Martinelli Boneschi F, Hauser SL, Oksenberg JR. Tranah GJ, et al. Among authors: santaniello a. Neurology. 2015 Jul 28;85(4):325-30. doi: 10.1212/WNL.0000000000001744. Epub 2015 Jul 1. Neurology. 2015. PMID: 26136518 Free PMC article.
An autoantibody signature predictive for multiple sclerosis.
Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Kizer K, Augusto DG, Tubati A, Gomez R, Fouassier C, Gerungan C, Caspar CM, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Sabatino JJ Jr, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BAC, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR. Zamecnik CR, et al. Among authors: santaniello a. Nat Med. 2024 May;30(5):1300-1308. doi: 10.1038/s41591-024-02938-3. Epub 2024 Apr 19. Nat Med. 2024. PMID: 38641750
163 results