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Page 1
Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae.
Ramos-Sevillano E, Ercoli G, Betts M, Guerra-Assunção JA, Iverson A, Frank M, Partridge F, Lo SW, Fernandes VE, Nasher F, Wall E, Wren B, Gordon SB, Ferreira DM, Heyderman R, Rosch J, Brown JS. Ramos-Sevillano E, et al. Among authors: guerra assuncao ja. mBio. 2024 Nov 13;15(11):e0175824. doi: 10.1128/mbio.01758-24. Epub 2024 Oct 18. mBio. 2024. PMID: 39422467 Free PMC article.
Mitochondrial dsRNA from B-ALL cells stimulates mesenchymal stromal cells to become cancer-associated fibroblasts.
Burt RJ, Dey A, Akarca A, Allen H, Amerikanou R, Atkinson S, Auty D, Chatzigerou J, Cutler E, Guerra-Assuncao JA, Kirschner K, Kumari R, Manji J, Marafioti T, Ward J, Fielding AK. Burt RJ, et al. Among authors: guerra assuncao ja. Blood Adv. 2024 Nov 12;8(21):5696-5709. doi: 10.1182/bloodadvances.2023012077. Blood Adv. 2024. PMID: 39226456 Free PMC article.
Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients.
Standing JF, Buggiotti L, Guerra-Assuncao JA, Woodall M, Ellis S, Agyeman AA, Miller C, Okechukwu M, Kirkpatrick E, Jacobs AI, Williams CA, Roy S, Martin-Bernal LM, Williams R, Smith CM, Sanderson T, Ashford FB, Emmanuel B, Afzal ZM, Shields A, Richter AG, Dorward J, Gbinigie O, Van Hecke O, Lown M, Francis N, Jani B, Richards DB, Rahman NM, Yu LM, Thomas NPB, Hart ND, Evans P, Andersson M, Hayward G, Hood K, Nguyen-Van-Tam JS, Little P, Hobbs FDR, Khoo S, Butler C, Lowe DM, Breuer J; PANORAMIC Virology Group. Standing JF, et al. Among authors: guerra assuncao ja. Nat Commun. 2024 Feb 23;15(1):1652. doi: 10.1038/s41467-024-45641-0. Nat Commun. 2024. PMID: 38396069 Free PMC article. Clinical Trial.
Genomic investigations of unexplained acute hepatitis in children.
Morfopoulou S, Buddle S, Torres Montaguth OE, Atkinson L, Guerra-Assunção JA, Moradi Marjaneh M, Zennezini Chiozzi R, Storey N, Campos L, Hutchinson JC, Counsell JR, Pollara G, Roy S, Venturini C, Antinao Diaz JF, Siam A, Tappouni LJ, Asgarian Z, Ng J, Hanlon KS, Lennon A, McArdle A, Czap A, Rosenheim J, Andrade C, Anderson G, Lee JCD, Williams R, Williams CA, Tutill H, Bayzid N, Martin Bernal LM, Macpherson H, Montgomery KA, Moore C, Templeton K, Neill C, Holden M, Gunson R, Shepherd SJ, Shah P, Cooray S, Voice M, Steele M, Fink C, Whittaker TE, Santilli G, Gissen P, Kaufer BB, Reich J, Andreani J, Simmonds P, Alrabiah DK, Castellano S, Chikowore P, Odam M, Rampling T, Houlihan C, Hoschler K, Talts T, Celma C, Gonzalez S, Gallagher E, Simmons R, Watson C, Mandal S, Zambon M, Chand M, Hatcher J, De S, Baillie K, Semple MG; DIAMONDS Consortium; PERFORM Consortium; ISARIC 4C Investigators; Martin J, Ushiro-Lumb I, Noursadeghi M, Deheragoda M, Hadzic N, Grammatikopoulos T, Brown R, Kelgeri C, Thalassinos K, Waddington SN, Jacques TS, Thomson E, Levin M, Brown JR, Breuer J. Morfopoulou S, et al. Among authors: guerra assuncao ja. Nature. 2023 May;617(7961):564-573. doi: 10.1038/s41586-023-06003-w. Epub 2023 Mar 30. Nature. 2023. PMID: 36996872 Free PMC article.
Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections.
Chandran A, Rosenheim J, Nageswaran G, Swadling L, Pollara G, Gupta RK, Burton AR, Guerra-Assunção JA, Woolston A, Ronel T, Pade C, Gibbons JM, Sanz-Magallon Duque De Estrada B, Robert de Massy M, Whelan M, Semper A, Brooks T, Altmann DM, Boyton RJ, McKnight Á, Captur G, Manisty C, Treibel TA, Moon JC, Tomlinson GS, Maini MK, Chain BM, Noursadeghi M; COVIDsortium Investigators. Chandran A, et al. Among authors: guerra assuncao ja. Cell Rep Med. 2022 Mar 4;3(3):100557. doi: 10.1016/j.xcrm.2022.100557. eCollection 2022 Mar 15. Cell Rep Med. 2022. PMID: 35474751 Free PMC article.
HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells.
Reuschl AK, Mesner D, Shivkumar M, Whelan MVX, Pallett LJ, Guerra-Assunção JA, Madansein R, Dullabh KJ, Sigal A, Thornhill JP, Herrera C, Fidler S, Noursadeghi M, Maini MK, Jolly C. Reuschl AK, et al. Among authors: guerra assuncao ja. Cell Rep. 2022 Apr 12;39(2):110650. doi: 10.1016/j.celrep.2022.110650. Cell Rep. 2022. PMID: 35417711 Free PMC article.
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.
Turati VA, Guerra-Assunção JA, Potter NE, Gupta R, Ecker S, Daneviciute A, Tarabichi M, Webster AP, Ding C, May G, James C, Brown J, Conde L, Russell LJ, Ancliff P, Inglott S, Cazzaniga G, Biondi A, Hall GW, Lynch M, Hubank M, Macaulay I, Beck S, Van Loo P, Jacobsen SE, Greaves M, Herrero J, Enver T. Turati VA, et al. Among authors: guerra assuncao ja. Nat Cancer. 2021 Aug;2(8):835-852. doi: 10.1038/s43018-021-00219-3. Epub 2021 Jul 5. Nat Cancer. 2021. PMID: 34734190 Free PMC article.
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