Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Xu X, Zhu XP, Bai JY, Xia P, Li Y, Lu Y, Li XY, Gao X.
Xu X, et al. Among authors: zhu xp.
FASEB J. 2019 Jun;33(6):7289-7300. doi: 10.1096/fj.201802316R. Epub 2019 Mar 8.
FASEB J. 2019.
PMID: 30848932
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, which may provide a novel mechanism and support BBR as a promising therapeutic for NAFLD.-Xu, X., Zhu, X.-P., Bai, J.-Y. …
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, w …