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A metabolome-derived score predicts metabolic dysfunction-associated steatohepatitis and mortality from liver disease.
Huang Q, Qadri SF, Bian H, Yi X, Lin C, Yang X, Zhu X, Lin H, Yan H, Chang X, Sun X, Ma S, Wu Q, Zeng H, Hu X, Zheng Y, Yki-Järvinen H, Gao X, Tang H, Xia M. Huang Q, et al. Among authors: zhu x. J Hepatol. 2024 Oct 16:S0168-8278(24)02636-9. doi: 10.1016/j.jhep.2024.10.015. Online ahead of print. J Hepatol. 2024. PMID: 39423864 Free article.
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Xu X, Zhu XP, Bai JY, Xia P, Li Y, Lu Y, Li XY, Gao X. Xu X, et al. Among authors: zhu xp. FASEB J. 2019 Jun;33(6):7289-7300. doi: 10.1096/fj.201802316R. Epub 2019 Mar 8. FASEB J. 2019. PMID: 30848932
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, which may provide a novel mechanism and support BBR as a promising therapeutic for NAFLD.-Xu, X., Zhu, X.-P., Bai, J.-Y. …
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, w …
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