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Page 1
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5.
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray JK, Ray C, Berenguer C, Kumari P, Bech JJ, Braun T, Ianni A, Tischfield JA, Serrano L, Esteller M, Sardina JL, De La Torre C, Sigvardsson M, Vazquez BN, Vaquero A. Gamez-Garcia A, et al. Among authors: thackray jk. Nat Immunol. 2024 Dec;25(12):2308-2319. doi: 10.1038/s41590-024-01995-7. Epub 2024 Oct 18. Nat Immunol. 2024. PMID: 39424985 Free PMC article.
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.
Vazquez BN, Thackray JK, Simonet NG, Kane-Goldsmith N, Martinez-Redondo P, Nguyen T, Bunting S, Vaquero A, Tischfield JA, Serrano L. Vazquez BN, et al. Among authors: thackray jk. EMBO J. 2016 Jul 15;35(14):1488-503. doi: 10.15252/embj.201593499. Epub 2016 May 24. EMBO J. 2016. PMID: 27225932 Free PMC article.
Sirtuins and DNA damage repair: SIRT7 comes to play.
Vazquez BN, Thackray JK, Serrano L. Vazquez BN, et al. Among authors: thackray jk. Nucleus. 2017 Mar 4;8(2):107-115. doi: 10.1080/19491034.2016.1264552. Epub 2017 Feb 17. Nucleus. 2017. PMID: 28406750 Free PMC article. Review.
SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1.
Simonet NG, Thackray JK, Vazquez BN, Ianni A, Espinosa-Alcantud M, Morales-Sanfrutos J, Hurtado-Bagès S, Sabidó E, Buschbeck M, Tischfield J, De La Torre C, Esteller M, Braun T, Olivella M, Serrano L, Vaquero A. Simonet NG, et al. Among authors: thackray jk. Sci Adv. 2020 Jul 24;6(30):eaaz2590. doi: 10.1126/sciadv.aaz2590. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832656 Free PMC article.
SIRT7 and p53 interaction in embryonic development and tumorigenesis.
Vazquez BN, Fernández-Duran I, Hernandez Y, Tarighi S, Thackray JK, Espinosa-Alcantud M, Kumari P, Ianni A, Cesaire L, Braun T, Esteller M, Tischfield J, Vaquero A, Serrano L. Vazquez BN, et al. Among authors: thackray jk. Front Cell Dev Biol. 2024 Jan 3;11:1281730. doi: 10.3389/fcell.2023.1281730. eCollection 2023. Front Cell Dev Biol. 2024. PMID: 38234684 Free PMC article.
Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization.
Bosch-Presegué L, Raurell-Vila H, Thackray JK, González J, Casal C, Kane-Goldsmith N, Vizoso M, Brown JP, Gómez A, Ausió J, Zimmermann T, Esteller M, Schotta G, Singh PB, Serrano L, Vaquero A. Bosch-Presegué L, et al. Among authors: thackray jk. Cell Rep. 2017 Nov 21;21(8):2048-2057. doi: 10.1016/j.celrep.2017.10.092. Cell Rep. 2017. PMID: 29166597 Free article.
Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.
Chahar S, Gandhi V, Yu S, Desai K, Cowper-Sal-lari R, Kim Y, Perekatt AO, Kumar N, Thackray JK, Musolf A, Kumar N, Hoffman A, Londono D, Vazquez BN, Serrano L, Shin H, Lupien M, Gao N, Verzi MP. Chahar S, et al. Among authors: thackray jk. Mol Cell Biol. 2014 Sep;34(17):3291-304. doi: 10.1128/MCB.00349-14. Epub 2014 Jun 30. Mol Cell Biol. 2014. PMID: 24980432 Free PMC article.
Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice.
Nasello C, Poppi LA, Wu J, Kowalski TF, Thackray JK, Wang R, Persaud A, Mahboob M, Lin S, Spaseska R, Johnson CK, Gordon D, Tissir F, Heiman GA, Tischfield JA, Bocarsly M, Tischfield MA. Nasello C, et al. Among authors: thackray jk. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2307156121. doi: 10.1073/pnas.2307156121. Epub 2024 Apr 29. Proc Natl Acad Sci U S A. 2024. PMID: 38683996 Free PMC article.
Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD.
Wang S, Wang B, Drury V, Drake S, Sun N, Alkhairo H, Arbelaez J, Duhn C; Tourette International Collaborative Genetics (TIC Genetics); Bal VH, Langley K, Martin J, Hoekstra PJ, Dietrich A, Xing J, Heiman GA, Tischfield JA, Fernandez TV, Owen MJ, O'Donovan MC, Thapar A, State MW, Willsey AJ. Wang S, et al. Nat Commun. 2023 Dec 6;14(1):8077. doi: 10.1038/s41467-023-43776-0. Nat Commun. 2023. PMID: 38057346 Free PMC article.
20 results