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A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5.
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray JK, Ray C, Berenguer C, Kumari P, Bech JJ, Braun T, Ianni A, Tischfield JA, Serrano L, Esteller M, Sardina JL, De La Torre C, Sigvardsson M, Vazquez BN, Vaquero A. Gamez-Garcia A, et al. Among authors: vaquero a. Nat Immunol. 2024 Dec;25(12):2308-2319. doi: 10.1038/s41590-024-01995-7. Epub 2024 Oct 18. Nat Immunol. 2024. PMID: 39424985 Free PMC article.
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.
Vazquez BN, Thackray JK, Simonet NG, Kane-Goldsmith N, Martinez-Redondo P, Nguyen T, Bunting S, Vaquero A, Tischfield JA, Serrano L. Vazquez BN, et al. Among authors: vaquero a. EMBO J. 2016 Jul 15;35(14):1488-503. doi: 10.15252/embj.201593499. Epub 2016 May 24. EMBO J. 2016. PMID: 27225932 Free PMC article.
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Santos-Barriopedro I, Bosch-Presegué L, Marazuela-Duque A, de la Torre C, Colomer C, Vazquez BN, Fuhrmann T, Martínez-Pastor B, Lu W, Braun T, Bober E, Jenuwein T, Serrano L, Esteller M, Chen Z, Barceló-Batllori S, Mostoslavsky R, Espinosa L, Vaquero A. Santos-Barriopedro I, et al. Among authors: vaquero a. Nat Commun. 2018 Jan 9;9(1):101. doi: 10.1038/s41467-017-02586-x. Nat Commun. 2018. PMID: 29317652 Free PMC article.
SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1.
Simonet NG, Thackray JK, Vazquez BN, Ianni A, Espinosa-Alcantud M, Morales-Sanfrutos J, Hurtado-Bagès S, Sabidó E, Buschbeck M, Tischfield J, De La Torre C, Esteller M, Braun T, Olivella M, Serrano L, Vaquero A. Simonet NG, et al. Among authors: vaquero a. Sci Adv. 2020 Jul 24;6(30):eaaz2590. doi: 10.1126/sciadv.aaz2590. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832656 Free PMC article.
SIRT7: a novel molecular target for personalized cancer treatment?
Ianni A, Kumari P, Tarighi S, Braun T, Vaquero A. Ianni A, et al. Among authors: vaquero a. Oncogene. 2024 Mar;43(14):993-1006. doi: 10.1038/s41388-024-02976-8. Epub 2024 Feb 21. Oncogene. 2024. PMID: 38383727 Free PMC article. Review.
SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.
Kumari P, Tarighi S, Fuchshuber E, Li L, Fernández-Duran I, Wang M, Ayoson J, Castelló-García JM, Gámez-García A, Espinosa-Alcantud M, Sreenivasan K, Guenther S, Olivella M, Savai R, Yue S, Vaquero A, Braun T, Ianni A. Kumari P, et al. Among authors: vaquero a. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2409269121. doi: 10.1073/pnas.2409269121. Epub 2024 Jun 13. Proc Natl Acad Sci U S A. 2024. PMID: 38870055 Free PMC article.
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation.
Serrano L, Martínez-Redondo P, Marazuela-Duque A, Vazquez BN, Dooley SJ, Voigt P, Beck DB, Kane-Goldsmith N, Tong Q, Rabanal RM, Fondevila D, Muñoz P, Krüger M, Tischfield JA, Vaquero A. Serrano L, et al. Among authors: vaquero a. Genes Dev. 2013 Mar 15;27(6):639-53. doi: 10.1101/gad.211342.112. Epub 2013 Mar 6. Genes Dev. 2013. PMID: 23468428 Free PMC article.
Sirtuins in female meiosis and in reproductive longevity.
Vazquez BN, Vaquero A, Schindler K. Vazquez BN, et al. Among authors: vaquero a. Mol Reprod Dev. 2020 Dec;87(12):1175-1187. doi: 10.1002/mrd.23437. Epub 2020 Nov 13. Mol Reprod Dev. 2020. PMID: 33184962 Free PMC article. Review.
115 results