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Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Hetzer SM, Patil SV, Di Polo A, Meyer JS. Huang KC, et al. Among authors: shiga y. Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2. Acta Neuropathol Commun. 2024. PMID: 39425218 Free PMC article.
Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Di Polo A, Meyer JS. Huang KC, et al. Among authors: shiga y. bioRxiv [Preprint]. 2023 Jan 4:2023.01.04.522687. doi: 10.1101/2023.01.04.522687. bioRxiv. 2023. Update in: Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2 PMID: 36711831 Free PMC article. Updated. Preprint.
Genetic Variants Associated With the Onset and Progression of Primary Open-Angle Glaucoma.
Mabuchi F, Mabuchi N, Sakurada Y, Yoneyama S, Kashiwagi K, Iijima H, Yamagata Z, Takamoto M, Aihara M, Iwata T, Hashimoto K, Sato K, Shiga Y, Nishiguchi KM, Nakazawa T, Akiyama M, Kawase K, Ozaki M, Araie M; Japan Glaucoma Society Omics Group (JGS-OG). Mabuchi F, et al. Among authors: shiga y. Am J Ophthalmol. 2020 Jul;215:135-140. doi: 10.1016/j.ajo.2020.03.014. Epub 2020 Mar 23. Am J Ophthalmol. 2020. PMID: 32217119
Fusobacterium nucleatum in the oral cavity is associated with cerebral small vessel disease in patients with ischemic stroke.
Aoki S, Nishi H, Shiga Y, Nezu T, Eto F, Imamura E, Shimomura R, Kawada-Matsuo M, Komatsuzawa H, Kawaguchi H, Maruyama H. Aoki S, et al. Among authors: shiga y. J Stroke Cerebrovasc Dis. 2024 Dec 6;34(1):108183. doi: 10.1016/j.jstrokecerebrovasdis.2024.108183. Online ahead of print. J Stroke Cerebrovasc Dis. 2024. PMID: 39647549 Free article.
Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma.
Diaz-Torres S, He W, Yu R; IGGC International Glaucoma Genetics Consortium; Khawaja AP, Hammond CJ, Hysi PG, Pasquale LR, Wu Y, Kubo M, Akiyama M, Aung T, Cheng CY, Khor CC, Kraft P, Kang JH, Hewitt AW, Mackey DA, Craig JE, Wiggs JL, Ong JS, MacGregor S, Gharahkhani P. Diaz-Torres S, et al. Nat Commun. 2024 Nov 17;15(1):9959. doi: 10.1038/s41467-024-54301-2. Nat Commun. 2024. PMID: 39551815 Free PMC article.
Radiographic Predictors of Lateral Translation in Patients With Residual Adolescent Idiopathic Scoliosis and Thoracolumbar/Lumbar Curves: A Focus on L3 Lateral Translation.
Mizutani M, Kotani T, Aoki Y, Iwata S, Okuwaki S, Ohyama S, Sakashita K, Ogata Y, Iijima Y, Sakuma T, Orita S, Inage K, Shiga Y, Minami S, Ohtori S. Mizutani M, et al. Among authors: shiga y. World Neurosurg. 2024 Nov 29:S1878-8750(24)01837-0. doi: 10.1016/j.wneu.2024.10.133. Online ahead of print. World Neurosurg. 2024. PMID: 39547330 Free article.
697 results