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Page 1
Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming.
Shen YR, Zaballa S, Bech X, Sancho-Balsells A, Rodríguez-Navarro I, Cifuentes-Díaz C, Seyit-Bremer G, Chun SH, Straub T, Abante J, Merino-Valverde I, Richart L, Gupta V, Li HY, Ballasch I, Alcázar N, Alberch J, Canals JM, Abad M, Serrano M, Klein R, Giralt A, Del Toro D. Shen YR, et al. Among authors: alcazar n. Cell Stem Cell. 2024 Dec 5;31(12):1741-1759.e8. doi: 10.1016/j.stem.2024.09.013. Epub 2024 Oct 18. Cell Stem Cell. 2024. PMID: 39426381 Free article.
The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling.
Plana-Carmona M, Stik G, Bulteau R, Segura-Morales C, Alcázar N, Wyatt CDR, Klonizakis A, de Andrés-Aguayo L, Gasnier M, Tian TV, Torcal Garcia G, Vila-Casadesús M, Plachta N, Serrano M, Francesconi M, Graf T. Plana-Carmona M, et al. Among authors: alcazar n. Stem Cell Reports. 2022 Sep 13;17(9):1991-2004. doi: 10.1016/j.stemcr.2022.07.009. Epub 2022 Aug 11. Stem Cell Reports. 2022. PMID: 35961310 Free PMC article.
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo.
Mosteiro L, Pantoja C, Alcazar N, Marión RM, Chondronasiou D, Rovira M, Fernandez-Marcos PJ, Muñoz-Martin M, Blanco-Aparicio C, Pastor J, Gómez-López G, De Martino A, Blasco MA, Abad M, Serrano M. Mosteiro L, et al. Among authors: alcazar n. Science. 2016 Nov 25;354(6315):aaf4445. doi: 10.1126/science.aaf4445. Science. 2016. PMID: 27884981
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M. Lynch CJ, et al. Among authors: alcazar n. Nat Cell Biol. 2020 Oct;22(10):1223-1238. doi: 10.1038/s41556-020-0573-1. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989249 Free article.
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness.
Benítez S, Cordero A, Santamaría PG, Redondo-Pedraza J, Rocha AS, Collado-Solé A, Jimenez M, Sanz-Moreno A, Yoldi G, Santos JC, De Benedictis I, Gómez-Aleza C, Da Silva-Álvarez S, Troulé K, Gómez-López G, Alcazar N, Palmero I, Collado M, Serrano M, Gonzalez-Suarez E. Benítez S, et al. Among authors: alcazar n. Dev Cell. 2021 Jun 21;56(12):1727-1741.e7. doi: 10.1016/j.devcel.2021.04.022. Epub 2021 May 17. Dev Cell. 2021. PMID: 34004159 Free PMC article.
Corrigendum to "Designing and evaluating an automated intravenous dosage medication calculation tool for reducing the time of stat medication administration in a pediatric emergency department" [Heliyon 6 (6) (June 2020) Article e04140].
AlGoraini Y, Hakeem N, AlShatarat M, Abudawass M, Azizalrahman A, Rehana R, Laderas D, AlCazar N, AlHarfi I. AlGoraini Y, et al. Among authors: alcazar n. Heliyon. 2020 Oct 7;6(10):e05064. doi: 10.1016/j.heliyon.2020.e05064. eCollection 2020 Oct. Heliyon. 2020. PMID: 33083592 Free PMC article.
Designing and evaluating an automated intravenous dosage medication calculation tool for reducing the time of stat medication administration in a pediatric emergency department.
AlGoraini Y, Hakeem N, AlShatarat M, Abudawass M, Azizalrahman A, Rehana R, Laderas D, AlCazar N, AlHarfi I. AlGoraini Y, et al. Among authors: alcazar n. Heliyon. 2020 Jun 4;6(6):e04140. doi: 10.1016/j.heliyon.2020.e04140. eCollection 2020 Jun. Heliyon. 2020. PMID: 32529084 Free PMC article.