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A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.
Menegakis A, Vennin C, Ient J, Groot AJ, Krenning L, Klompmaker R, Friskes A, Ilic M, Yaromina A, Harkes R, van den Broek B, Jakob Sonke J, De Jong M, Piepers J, van Rheenen J, Vooijs MA, Medema RH. Menegakis A, et al. Among authors: ient j. Radiother Oncol. 2025 Jan;202:110592. doi: 10.1016/j.radonc.2024.110592. Epub 2024 Oct 18. Radiother Oncol. 2025. PMID: 39427933 Free PMC article.
A lineage-tracing tool to map the fate of hypoxic tumour cells.
Vermeer JAF, Ient J, Markelc B, Kaeppler J, Barbeau LMO, Groot AJ, Muschel RJ, Vooijs MA. Vermeer JAF, et al. Among authors: ient j. Dis Model Mech. 2020 Jul 30;13(7):dmm044768. doi: 10.1242/dmm.044768. Dis Model Mech. 2020. PMID: 32571767 Free PMC article.
Radiation-Induced Lung Injury (RILI).
Giuranno L, Ient J, De Ruysscher D, Vooijs MA. Giuranno L, et al. Among authors: ient j. Front Oncol. 2019 Sep 6;9:877. doi: 10.3389/fonc.2019.00877. eCollection 2019. Front Oncol. 2019. PMID: 31555602 Free PMC article. Review.
HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells.
Moreno Roig E, Groot AJ, Yaromina A, Hendrickx TC, Barbeau LMO, Giuranno L, Dams G, Ient J, Olivo Pimentel V, van Gisbergen MW, Dubois LJ, Vooijs MA. Moreno Roig E, et al. Among authors: ient j. Cells. 2019 Jan 12;8(1):45. doi: 10.3390/cells8010045. Cells. 2019. PMID: 30642030 Free PMC article.
Moving Breast Cancer Therapy up a Notch.
Mollen EWJ, Ient J, Tjan-Heijnen VCG, Boersma LJ, Miele L, Smidt ML, Vooijs MAGG. Mollen EWJ, et al. Among authors: ient j. Front Oncol. 2018 Nov 20;8:518. doi: 10.3389/fonc.2018.00518. eCollection 2018. Front Oncol. 2018. PMID: 30515368 Free PMC article. Review.