van den Broek B - Search Results

1

A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.

Menegakis A, Vennin C, Ient J, Groot AJ, Krenning L, Klompmaker R, Friskes A, Ilic M, Yaromina A, Harkes R, van den Broek B, Jakob Sonke J, De Jong M, Piepers J, van Rheenen J, Vooijs MA, Medema RH. Menegakis A, et al. Among authors: van den broek b. Radiother Oncol. 2025 Jan;202:110592. doi: 10.1016/j.radonc.2024.110592. Epub 2024 Oct 18. Radiother Oncol. 2025. PMID: 39427933 Free PMC article.

2

Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence.

Menegakis A, Klompmaker R, Vennin C, Arbusà A, Damen M, van den Broek B, Zips D, van Rheenen J, Krenning L, Medema RH. Menegakis A, et al. Among authors: van den broek b, van rheenen j. Cells. 2021 Mar 10;10(3):610. doi: 10.3390/cells10030610. Cells. 2021. PMID: 33801903 Free PMC article.

3

MND1 enables homologous recombination in somatic cells primarily outside the context of replication.

Koob L, Friskes A, van Bergen L, Feringa FM, van den Broek B, Koeleman ES, van Beek E, Schubert M, Blomen VA, Brummelkamp TR, Krenning L, Medema RH. Koob L, et al. Among authors: van beek e, van den broek b, van bergen l. Mol Oncol. 2023 Jul;17(7):1192-1211. doi: 10.1002/1878-0261.13448. Epub 2023 Jun 14. Mol Oncol. 2023. PMID: 37195379 Free PMC article.

4

Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.

Feringa FM, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, Medema RH. Feringa FM, et al. Among authors: van den berg j, van den broek b. Nat Commun. 2016 Aug 26;7:12618. doi: 10.1038/ncomms12618. Nat Commun. 2016. PMID: 27561326 Free PMC article.

5

Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells.

García-Santisteban I, Llopis A, Krenning L, Vallejo-Rodríguez J, van den Broek B, Zubiaga AM, Medema RH. García-Santisteban I, et al. Among authors: van den broek b. BMC Biol. 2021 Feb 19;19(1):35. doi: 10.1186/s12915-021-00965-x. BMC Biol. 2021. PMID: 33607997 Free PMC article.

6

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

Tame MA, Raaijmakers JA, van den Broek B, Lindqvist A, Jalink K, Medema RH. Tame MA, et al. Among authors: van den broek b. Cell Cycle. 2014;13(7):1162-70. doi: 10.4161/cc.28031. Epub 2014 Feb 10. Cell Cycle. 2014. PMID: 24553118 Free PMC article.

7

Dynamic FRET-FLIM based screening of signal transduction pathways.

Harkes R, Kukk O, Mukherjee S, Klarenbeek J, van den Broek B, Jalink K. Harkes R, et al. Among authors: van den broek b. Sci Rep. 2021 Oct 20;11(1):20711. doi: 10.1038/s41598-021-00098-9. Sci Rep. 2021. PMID: 34671065 Free PMC article.

8

WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy.

Haarhuis JH, Elbatsh AM, van den Broek B, Camps D, Erkan H, Jalink K, Medema RH, Rowland BD. Haarhuis JH, et al. Among authors: van den broek b. Curr Biol. 2013 Oct 21;23(20):2071-7. doi: 10.1016/j.cub.2013.09.003. Epub 2013 Sep 19. Curr Biol. 2013. PMID: 24055153 Free article.

9

Doxorubicin-induced DNA Damage Causes Extensive Ubiquitination of Ribosomal Proteins Associated with a Decrease in Protein Translation.

Halim VA, García-Santisteban I, Warmerdam DO, van den Broek B, Heck AJR, Mohammed S, Medema RH. Halim VA, et al. Among authors: van den broek b. Mol Cell Proteomics. 2018 Dec;17(12):2297-2308. doi: 10.1074/mcp.RA118.000652. Epub 2018 Feb 8. Mol Cell Proteomics. 2018. PMID: 29438997 Free PMC article.

10

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

Vizoso M, E J Pritchard C, Bombardelli L, van den Broek B, Krimpenfort P, Beijersbergen RL, Jalink K, van Rheenen J. Vizoso M, et al. Among authors: van den broek b, van rheenen j. Nat Commun. 2022 Oct 28;13(1):6442. doi: 10.1038/s41467-022-33863-z. Nat Commun. 2022. PMID: 36307419 Free PMC article.

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