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Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
Wang T, Wang B, Huang H, Zhang C, Zhu Y, Pei B, Cheng C, Sun L, Wang J, Jin Q, Zhao Z. Wang T, et al. Among authors: huang h. PLoS Pathog. 2017 Oct 6;13(10):e1006674. doi: 10.1371/journal.ppat.1006674. eCollection 2017 Oct. PLoS Pathog. 2017. PMID: 28985237 Free PMC article.
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