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Preexisting risk-avoidance and enhanced alcohol relief are driven by imbalance of the striatal dopamine receptors in mice.
Bocarsly ME, Shaw MJ, Ventriglia E, Anderson LG, Goldbach HC, Teresi CE, Bravo M, Bock R, Hong P, Kwon HB, Khawaja IM, Raman R, Murray EM, Bonaventura J, Burke DA, Michaelides M, Alvarez VA. Bocarsly ME, et al. Among authors: bonaventura j. Nat Commun. 2024 Oct 22;15(1):9093. doi: 10.1038/s41467-024-53414-y. Nat Commun. 2024. PMID: 39438478 Free PMC article.
Motivational valence is determined by striatal melanocortin 4 receptors.
Klawonn AM, Fritz M, Nilsson A, Bonaventura J, Shionoya K, Mirrasekhian E, Karlsson U, Jaarola M, Granseth B, Blomqvist A, Michaelides M, Engblom D. Klawonn AM, et al. Among authors: bonaventura j. J Clin Invest. 2018 Jul 2;128(7):3160-3170. doi: 10.1172/JCI97854. Epub 2018 Jun 18. J Clin Invest. 2018. PMID: 29911992 Free PMC article.
A non-canonical striatopallidal Go pathway that supports motor control.
Labouesse MA, Torres-Herraez A, Chohan MO, Villarin JM, Greenwald J, Sun X, Zahran M, Tang A, Lam S, Veenstra-VanderWeele J, Lacefield CO, Bonaventura J, Michaelides M, Chan CS, Yizhar O, Kellendonk C. Labouesse MA, et al. Among authors: bonaventura j. Nat Commun. 2023 Oct 23;14(1):6712. doi: 10.1038/s41467-023-42288-1. Nat Commun. 2023. PMID: 37872145 Free PMC article.
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior.
Gomez JL, Bonaventura J, Keighron J, Wright KM, Marable DL, Rodriguez LA, Lam S, Carlton ML, Ellis RJ, Jordan CJ, Bi GH, Solis O, Pignatelli M, Bannon MJ, Xi ZX, Tanda G, Michaelides M. Gomez JL, et al. Among authors: bonaventura j. Transl Psychiatry. 2021 Nov 8;11(1):570. doi: 10.1038/s41398-021-01693-0. Transl Psychiatry. 2021. PMID: 34750356 Free PMC article.
Essential role of P-glycoprotein in the mechanism of action of oliceridine.
Ventriglia E, Rizzo A, Gomez JL, Friedman J, Lam S, Solís O, Rais R, Bonaventura J, Michaelides M. Ventriglia E, et al. Among authors: bonaventura j. Neuropsychopharmacology. 2023 Apr;48(5):831-842. doi: 10.1038/s41386-022-01507-x. Epub 2022 Nov 25. Neuropsychopharmacology. 2023. PMID: 36434081 Free PMC article.
Adolescent nicotine administration increases nicotinic acetylcholine receptor binding and functional connectivity in specific cortico-striatal-thalamic circuits.
Keeley RJ, Prillaman ME, Scarlata M, Vrana A, Tsai PJ, Gomez JL, Bonaventura J, Lu H, Michaelides M, Stein EA. Keeley RJ, et al. Among authors: bonaventura j. Brain Commun. 2022 Nov 19;4(6):fcac291. doi: 10.1093/braincomms/fcac291. eCollection 2022. Brain Commun. 2022. PMID: 36440101 Free PMC article.
High-potency ligands for DREADD imaging and activation in rodents and monkeys.
Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M. Bonaventura J, et al. Nat Commun. 2019 Oct 11;10(1):4627. doi: 10.1038/s41467-019-12236-z. Nat Commun. 2019. PMID: 31604917 Free PMC article.
In vivo photopharmacology with light-activated opioid drugs.
McClain SP, Ma X, Johnson DA, Johnson CA, Layden AE, Yung JC, Lubejko ST, Livrizzi G, He XJ, Zhou J, Chang-Weinberg J, Ventriglia E, Rizzo A, Levinstein M, Gomez JL, Bonaventura J, Michaelides M, Banghart MR. McClain SP, et al. Among authors: bonaventura j. Neuron. 2023 Dec 20;111(24):3926-3940.e10. doi: 10.1016/j.neuron.2023.09.017. Epub 2023 Oct 16. Neuron. 2023. PMID: 37848025 Free PMC article.
229 results