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A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl Immunity.
Zhong Z, Deventer MH, Chen Y, Vanhee S, Lammens I, Deswarte K, Huang Y, Ye T, Wang H, Nuhn L, Vandeputte MM, Gontsarik M, Cui X, Sanders NN, Lienenklaus S, N Lambrecht B, Baptista AP, Stove CP, G De Geest B. Zhong Z, et al. Among authors: ye t. Angew Chem Int Ed Engl. 2024 Oct 23:e202419031. doi: 10.1002/anie.202419031. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39441822
Current Status of COVID-19 (Pre)Clinical Vaccine Development.
Ye T, Zhong Z, García-Sastre A, Schotsaert M, De Geest BG. Ye T, et al. Angew Chem Int Ed Engl. 2020 Oct 19;59(43):18885-18897. doi: 10.1002/anie.202008319. Epub 2020 Sep 2. Angew Chem Int Ed Engl. 2020. PMID: 32663348 Free PMC article. Review.
Lipid-Polyglutamate Nanoparticle Vaccine Platform.
Van Lysebetten D, Malfanti A, Deswarte K, Koynov K, Golba B, Ye T, Zhong Z, Kasmi S, Lamoot A, Chen Y, Van Herck S, Lambrecht BN, Sanders NN, Lienenklaus S, David SA, Vicent MJ, De Koker S, De Geest BG. Van Lysebetten D, et al. Among authors: ye t. ACS Appl Mater Interfaces. 2021 Feb 10;13(5):6011-6022. doi: 10.1021/acsami.0c20607. Epub 2021 Jan 28. ACS Appl Mater Interfaces. 2021. PMID: 33507728 Free PMC article.
Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Lamoot A, Jangra S, Laghlali G, Warang P, Singh G, Chang LA, Park SC, Singh G, De Swarte K, Zhong Z, Louage B, De Lombaerde E, Ye T, Chen Y, Cuadrado-Castano S, Lienenklaus S, Sanders NN, Lambrecht BN, García-Sastre A, Schotsaert M, De Geest BG. Lamoot A, et al. Among authors: ye t. Small. 2024 Mar;20(10):e2306892. doi: 10.1002/smll.202306892. Epub 2023 Oct 22. Small. 2024. PMID: 37867244 Free PMC article.
CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity.
Ye T, Zhong Z, Cappellesso F, Deswarte K, Chen Y, Lauwers H, De Lombaerde E, Gontsarik M, Lienenklaus S, Van Lysebetten D, Sanders NN, Lambrecht BN, De Koker S, Laoui D, De Geest BG. Ye T, et al. Biomaterials. 2024 Dec;311:122693. doi: 10.1016/j.biomaterials.2024.122693. Epub 2024 Jun 27. Biomaterials. 2024. PMID: 38996672
Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity.
Cigrang M, Obid J, Nogaret M, Seno L, Ye T, Davidson G, Catez P, Berico P, Capelli C, Marechal C, Zachayus A, Elly C, Guillen Navarro MJ, Martinez Diez M, Santamaria Nunez G, Li TK, Compe E, Avilés P, Davidson I, Egly JM, Cuevas C, Coin F. Cigrang M, et al. Among authors: ye t. Nat Commun. 2025 Jan 8;16(1):512. doi: 10.1038/s41467-024-55667-z. Nat Commun. 2025. PMID: 39779693 Free PMC article.
2,796 results