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TP53: the unluckiest of genes?
Joerger AC, Stiewe T, Soussi T. Joerger AC, et al. Cell Death Differ. 2024 Oct 23. doi: 10.1038/s41418-024-01391-6. Online ahead of print. Cell Death Differ. 2024. PMID: 39443700 Review.
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.
Doffe F, Carbonnier V, Tissier M, Leroy B, Martins I, Mattsson JSM, Micke P, Pavlova S, Pospisilova S, Smardova J, Joerger AC, Wiman KG, Kroemer G, Soussi T. Doffe F, et al. Among authors: joerger ac. Cell Death Differ. 2021 May;28(5):1477-1492. doi: 10.1038/s41418-020-00672-0. Epub 2020 Nov 30. Cell Death Differ. 2021. PMID: 33257846 Free PMC article.
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Funk JS, Klimovich M, Drangenstein D, Pielhoop O, Hunold P, Borowek A, Noeparast M, Pavlakis E, Neumann M, Balourdas DI, Kochhan K, Merle N, Bullwinkel I, Wanzel M, Elmshäuser S, Teply-Szymanski J, Nist A, Procida T, Bartkuhn M, Humpert K, Mernberger M, Savai R, Soussi T, Joerger AC, Stiewe T. Funk JS, et al. Among authors: joerger ac. Nat Genet. 2025 Jan;57(1):140-153. doi: 10.1038/s41588-024-02039-4. Epub 2025 Jan 7. Nat Genet. 2025. PMID: 39774325 Free PMC article.
DARPin-induced reactivation of p53 in HPV-positive cells.
Münick P, Strubel A, Balourdas DI, Funk JS, Mernberger M, Osterburg C, Dreier B, Schaefer JV, Tuppi M, Yüksel B, Schäfer B, Knapp S, Plückthun A, Stiewe T, Joerger AC, Dötsch V. Münick P, et al. Among authors: joerger ac. Nat Struct Mol Biol. 2025 Jan 9. doi: 10.1038/s41594-024-01456-7. Online ahead of print. Nat Struct Mol Biol. 2025. PMID: 39789211
Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
Wanior M, Preuss F, Ni X, Krämer A, Mathea S, Göbel T, Heidenreich D, Simonyi S, Kahnt AS, Joerger AC, Knapp S. Wanior M, et al. Among authors: joerger ac. J Med Chem. 2020 Dec 10;63(23):14680-14699. doi: 10.1021/acs.jmedchem.0c01242. Epub 2020 Nov 20. J Med Chem. 2020. PMID: 33216538
70 results