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Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin.
Turner AM, Li L, Monk IR, Lee JYH, Ingle DJ, Portelli S, Sherry NL, Isles N, Seemann T, Sharkey LK, Walsh CJ, Reid GE, Nie S, Eijkelkamp BA, Holmes NE, Collis B, Vogrin S, Hiergeist A, Weber D, Gessner A, Holler E, Ascher DB, Duchene S, Scott NE, Stinear TP, Kwong JC, Gorrie CL, Howden BP, Carter GP. Turner AM, et al. Among authors: walsh cj. Nature. 2024 Nov;635(8040):969-977. doi: 10.1038/s41586-024-08095-4. Epub 2024 Oct 23. Nature. 2024. PMID: 39443798 Free PMC article.
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.
Mu A, Klare WP, Baines SL, Ignatius Pang CN, Guérillot R, Harbison-Price N, Keller N, Wilksch J, Nhu NTK, Phan MD, Keller B, Nijagal B, Tull D, Dayalan S, Chua HHC, Skoneczny D, Koval J, Hachani A, Shah AD, Neha N, Jadhav S, Partridge SR, Cork AJ, Peters K, Bertolla O, Brouwer S, Hancock SJ, Álvarez-Fraga L, De Oliveira DMP, Forde B, Dale A, Mujchariyakul W, Walsh CJ, Monk I, Fitzgerald A, Lum M, Correa-Ospina C, Roy Chowdhury P, Parton RG, De Voss J, Beckett J, Monty F, McKinnon J, Song X, Stephen JR, Everest M, Bellgard MI, Tinning M, Leeming M, Hocking D, Jebeli L, Wang N, Ben Zakour N, Yasar SA, Vecchiarelli S, Russell T, Zaw T, Chen T, Teng D, Kassir Z, Lithgow T, Jenney A, Cole JN, Nizet V, Sorrell TC, Peleg AY, Paterson DL, Beatson SA, Wu J, Molloy MP, Syme AE, Goode RJA, Hunter AA, Bowland G, West NP, Wilkins MR, Djordjevic SP, Davies MR, Seemann T, Howden BP, Pascovici D, Tyagi S, Schittenhelm RB, De Souza DP, McConville MJ, Iredell JR, Cordwell SJ, Strugnell RA, Stinear TP, Schembri MA, Walker MJ. Mu A, et al. Among authors: walsh cj. Nat Commun. 2023 Mar 18;14(1):1530. doi: 10.1038/s41467-023-37200-w. Nat Commun. 2023. PMID: 36934086 Free PMC article.
The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in Staphylococcus aureus.
Sharkey LKR, Guerillot R, Walsh CJ, Turner AM, Lee JYH, Neville SL, Klatt S, Baines SL, Pidot SJ, Rossello FJ, Seemann T, McWilliam HEG, Cho E, Carter GP, Howden BP, McDevitt CA, Hachani A, Stinear TP, Monk IR. Sharkey LKR, et al. Among authors: walsh cj. mBio. 2023 Dec 19;14(6):e0226223. doi: 10.1128/mbio.02262-23. Epub 2023 Oct 16. mBio. 2023. PMID: 37850732 Free PMC article.
A high-throughput cytotoxicity screening platform reveals agr-independent mutations in bacteraemia-associated Staphylococcus aureus that promote intracellular persistence.
Hachani A, Giulieri SG, Guérillot R, Walsh CJ, Herisse M, Soe YM, Baines SL, Thomas DR, Cheung SD, Hayes AS, Cho E, Newton HJ, Pidot S, Massey RC, Howden BP, Stinear TP. Hachani A, et al. Among authors: walsh cj. Elife. 2023 Jun 8;12:e84778. doi: 10.7554/eLife.84778. Elife. 2023. PMID: 37289634 Free PMC article.
Retinoic acid and TGF-β orchestrate organ-specific programs of tissue residency.
Obers A, Poch T, Rodrigues G, Christo SN, Gandolfo LC, Fonseca R, Zaid A, Kuai JEY, Lai H, Zareie P, Yakou MH, Dryburgh L, Burn TN, Dosser J, Buquicchio FA, Lareau CA, Walsh C, Judd L, Theodorou MR, Gutbrod K, Dörmann P, Kingham J, Stinear T, Kallies A, Schroeder J, Mueller SN, Park SL, Speed TP, Satpathy AT, Phan TG, Wilhelm C, Zaph C, Evrard M, Mackay LK. Obers A, et al. Immunity. 2024 Nov 12;57(11):2615-2633.e10. doi: 10.1016/j.immuni.2024.09.015. Epub 2024 Oct 14. Immunity. 2024. PMID: 39406245
Dietary amino acids, macronutrients, vaginal birth, and breastfeeding are associated with the vaginal microbiome in early pregnancy.
Corbett GA, Moore R, Feehily C, Killeen SL, O'Brien E, Van Sinderen D, Matthews E, O'Flaherty R, Rudd PM, Saldova R, Walsh CJ, Lawton EM, MacIntyre DA, Corcoran S, Cotter PD, McAuliffe FM. Corbett GA, et al. Among authors: walsh cj. Microbiol Spectr. 2024 Nov 5;12(11):e0113024. doi: 10.1128/spectrum.01130-24. Epub 2024 Oct 4. Microbiol Spectr. 2024. PMID: 39365058 Free PMC article.
275 results