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Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS.
Sandoval IM, Kelley CM, Bernal-Conde LD, Steece-Collier K, Marmion DJ, Davidsson M, Crosson SM, Boye SL, Boye SE, Manfredsson FP. Sandoval IM, et al. Among authors: boye se. Mol Ther Nucleic Acids. 2024 Sep 12;35(4):102332. doi: 10.1016/j.omtn.2024.102332. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39445231 Free PMC article.
Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa.
Pang JJ, Dai X, Boye SE, Barone I, Boye SL, Mao S, Everhart D, Dinculescu A, Liu L, Umino Y, Lei B, Chang B, Barlow R, Strettoi E, Hauswirth WW. Pang JJ, et al. Among authors: boye sl, boye se. Mol Ther. 2011 Feb;19(2):234-42. doi: 10.1038/mt.2010.273. Epub 2010 Dec 7. Mol Ther. 2011. PMID: 21139570 Free PMC article.
Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness.
Doroudchi MM, Greenberg KP, Liu J, Silka KA, Boyden ES, Lockridge JA, Arman AC, Janani R, Boye SE, Boye SL, Gordon GM, Matteo BC, Sampath AP, Hauswirth WW, Horsager A. Doroudchi MM, et al. Among authors: boye sl, boye se. Mol Ther. 2011 Jul;19(7):1220-9. doi: 10.1038/mt.2011.69. Epub 2011 Apr 19. Mol Ther. 2011. PMID: 21505421 Free PMC article.
A comprehensive review of retinal gene therapy.
Boye SE, Boye SL, Lewin AS, Hauswirth WW. Boye SE, et al. Among authors: boye sl. Mol Ther. 2013 Mar;21(3):509-19. doi: 10.1038/mt.2012.280. Epub 2013 Jan 29. Mol Ther. 2013. PMID: 23358189 Free PMC article. Review.
78 results