Sinclair J - Search Results

1

Virus-Specific Nanobody-Chimeras Degrade the Human Cytomegalovirus US28 Protein in CD34+ Cells.

Poole E, Schmitt J, Graham SC, Kelly BT, Sinclair J. Poole E, et al. Among authors: sinclair j. Pathogens. 2024 Sep 24;13(10):821. doi: 10.3390/pathogens13100821. Pathogens. 2024. PMID: 39452693 Free PMC article.

2

Understanding HCMV Latency Using Unbiased Proteomic Analyses.

Poole E, Sinclair J. Poole E, et al. Among authors: sinclair j. Pathogens. 2020 Jul 20;9(7):590. doi: 10.3390/pathogens9070590. Pathogens. 2020. PMID: 32698381 Free PMC article. Review.

3

The UL144 gene product of human cytomegalovirus activates NFkappaB via a TRAF6-dependent mechanism.

Poole E, King CA, Sinclair JH, Alcami A. Poole E, et al. EMBO J. 2006 Sep 20;25(18):4390-9. doi: 10.1038/sj.emboj.7601287. Epub 2006 Aug 24. EMBO J. 2006. PMID: 16932746 Free PMC article.

4

Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34⁺ progenitors.

Poole E, McGregor Dallas SR, Colston J, Joseph RSV, Sinclair J. Poole E, et al. Among authors: sinclair j. J Gen Virol. 2011 Jul;92(Pt 7):1539-1549. doi: 10.1099/vir.0.031377-0. Epub 2011 Apr 6. J Gen Virol. 2011. PMID: 21471310

5

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function.

Mason GM, Poole E, Sissons JG, Wills MR, Sinclair JH. Mason GM, et al. Among authors: sinclair jh. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14538-43. doi: 10.1073/pnas.1204836109. Epub 2012 Jul 23. Proc Natl Acad Sci U S A. 2012. PMID: 22826250 Free PMC article.

6

The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirus.

Poole E, Bain M, Teague L, Takei Y, Laskey R, Sinclair J. Poole E, et al. Among authors: sinclair j. PLoS One. 2012;7(10):e45686. doi: 10.1371/journal.pone.0045686. Epub 2012 Oct 19. PLoS One. 2012. PMID: 23094019 Free PMC article.

7

Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells.

Mason GM, Jackson S, Okecha G, Poole E, Sissons JG, Sinclair J, Wills MR. Mason GM, et al. Among authors: sinclair j. PLoS Pathog. 2013;9(10):e1003635. doi: 10.1371/journal.ppat.1003635. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130479 Free PMC article. Clinical Trial.

8

The use of primary human cells (fibroblasts, monocytes, and others) to assess human cytomegalovirus function.

Poole E, Reeves M, Sinclair JH. Poole E, et al. Methods Mol Biol. 2014;1119:81-98. doi: 10.1007/978-1-62703-788-4_6. Methods Mol Biol. 2014. PMID: 24639219

9

Sleepless latency of human cytomegalovirus.

Poole E, Sinclair J. Poole E, et al. Among authors: sinclair j. Med Microbiol Immunol. 2015 Jun;204(3):421-9. doi: 10.1007/s00430-015-0401-6. Epub 2015 Mar 14. Med Microbiol Immunol. 2015. PMID: 25772624 Free PMC article. Review.

10

Latent infection of myeloid progenitors by human cytomegalovirus protects cells from FAS-mediated apoptosis through the cellular IL-10/PEA-15 pathway.

Poole E, Lau JCH, Sinclair J. Poole E, et al. Among authors: sinclair j. J Gen Virol. 2015 Aug;96(8):2355-2359. doi: 10.1099/vir.0.000180. Epub 2015 May 8. J Gen Virol. 2015. PMID: 25957098 Free PMC article.

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