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Page 1
Targeting KDM1A in Neuroblastoma with NCL-1 Induces a Less Aggressive Phenotype and Suppresses Angiogenesis.
Sprüssel A, Suzuki T, Miyata N, Astrahantseff K, Szymansky A, Toedling J, Thole-Kliesch TM, Ballagee A, Lodrini M, Künkele A, Truss M, Heukamp LC, Mathia S, Hertwig F, Rosenberger C, Eggert A, Deubzer HE, Schulte JH. Sprüssel A, et al. J Clin Med. 2024 Oct 12;13(20):6081. doi: 10.3390/jcm13206081. J Clin Med. 2024. PMID: 39458030 Free PMC article.
Circulating Cell-Free DNA Assessment in Biofluids from Children with Neuroblastoma Demonstrates Feasibility and Potential for Minimally Invasive Molecular Diagnostics.
Lodrini M, Wünschel J, Thole-Kliesch TM, Grimaldi M, Sprüssel A, Linke RB, Hollander JF, Tiburtius D, Künkele A, Schulte JH, Lankes E, Elgeti T, Hundsdörfer P, Astrahantseff K, Simon T, Eggert A, Deubzer HE. Lodrini M, et al. Among authors: sprussel a. Cancers (Basel). 2022 Apr 21;14(9):2080. doi: 10.3390/cancers14092080. Cancers (Basel). 2022. PMID: 35565208 Free PMC article.
Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma.
Lodrini M, Graef J, Thole-Kliesch TM, Astrahantseff K, Sprüssel A, Grimaldi M, Peitz C, Linke RB, Hollander JF, Lankes E, Künkele A, Oevermann L, Schwabe G, Fuchs J, Szymansky A, Schulte JH, Hundsdörfer P, Eckert C, Amthauer H, Eggert A, Deubzer HE. Lodrini M, et al. Among authors: sprussel a. Clin Cancer Res. 2022 May 2;28(9):1809-1820. doi: 10.1158/1078-0432.CCR-21-3716. Clin Cancer Res. 2022. PMID: 35247920
Multiplexed Quantification of Four Neuroblastoma DNA Targets in a Single Droplet Digital PCR Reaction.
Peitz C, Sprüssel A, Linke RB, Astrahantseff K, Grimaldi M, Schmelz K, Toedling J, Schulte JH, Fischer M, Messerschmidt C, Beule D, Keilholz U, Eggert A, Deubzer HE, Lodrini M. Peitz C, et al. Among authors: sprussel a. J Mol Diagn. 2020 Nov;22(11):1309-1323. doi: 10.1016/j.jmoldx.2020.07.006. Epub 2020 Aug 26. J Mol Diagn. 2020. PMID: 32858250 Free article.
Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole TM, Toedling J, Sprüssel A, Pfeil S, Savelyeva L, Capper D, Messerschmidt C, Beule D, Groeneveld-Krentz S, Eckert C, Gambara G, Henssen AG, Finkler S, Schulte JH, Sieber A, Bluethgen N, Regenbrecht CRA, Künkele A, Lodrini M, Eggert A, Deubzer HE. Thole TM, et al. Among authors: sprussel a. Int J Cancer. 2020 Feb 15;146(4):1031-1041. doi: 10.1002/ijc.32572. Epub 2019 Aug 1. Int J Cancer. 2020. PMID: 31304977
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler KW, Sadowski N, Ackermann S, Althoff K, Schönbeck K, Batzke K, Schäfers S, Odersky A, Heukamp L, Astrahantseff K, Künkele A, Deubzer HE, Schramm A, Sprüssel A, Thor T, Lindner S, Eggert A, Fischer M, Schulte JH. Pajtler KW, et al. Among authors: sprussel a. Oncotarget. 2017 Jan 24;8(4):6730-6741. doi: 10.18632/oncotarget.14268. Oncotarget. 2017. PMID: 28036269 Free PMC article.
A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.
Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprüssel A, Lindner S, De Preter K, Florin A, Heukamp LC, Klein-Hitpass L, Astrahantseff K, Kumps C, Speleman F, Eggert A, Westermann F, Schramm A, Schulte JH. Althoff K, et al. Among authors: sprussel a. Oncogene. 2015 Jun;34(26):3357-68. doi: 10.1038/onc.2014.269. Epub 2014 Sep 1. Oncogene. 2015. PMID: 25174395 Free PMC article.
MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.
Althoff K, Beckers A, Odersky A, Mestdagh P, Köster J, Bray IM, Bryan K, Vandesompele J, Speleman F, Stallings RL, Schramm A, Eggert A, Sprüssel A, Schulte JH. Althoff K, et al. Among authors: sprussel a. Int J Cancer. 2013 Sep 1;133(5):1064-73. doi: 10.1002/ijc.28091. Epub 2013 Mar 7. Int J Cancer. 2013. PMID: 23400681
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