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Non-lytic spread of poliovirus requires the nonstructural protein 3CD.
Aponte-Diaz D, Harris JM, Kang TE, Korboukh V, Sotoudegan MS, Gray JL, Yennawar NH, Moustafa IM, Macadam A, Cameron CE. Aponte-Diaz D, et al. Among authors: macadam a. bioRxiv [Preprint]. 2024 Oct 19:2024.10.18.619132. doi: 10.1101/2024.10.18.619132. bioRxiv. 2024. Update in: mBio. 2025 Jan 8;16(1):e0327624. doi: 10.1128/mbio.03276-24 PMID: 39464037 Free PMC article. Updated. Preprint.
Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis.
Shen L, Chen CY, Huang D, Wang R, Zhang M, Qian L, Zhu Y, Zhang AZ, Yang E, Qaqish A, Chumakov K, Kouiavskaia D, Vignuzzi M, Nathanson N, Macadam AJ, Andino R, Kew O, Xu J, Chen ZW. Shen L, et al. Among authors: macadam aj. J Virol. 2017 Jun 26;91(14):e02310-16. doi: 10.1128/JVI.02310-16. Print 2017 Jul 15. J Virol. 2017. PMID: 28356537 Free PMC article.
The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study.
Van Damme P, De Coster I, Bandyopadhyay AS, Revets H, Withanage K, De Smedt P, Suykens L, Oberste MS, Weldon WC, Costa-Clemens SA, Clemens R, Modlin J, Weiner AJ, Macadam AJ, Andino R, Kew OM, Konopka-Anstadt JL, Burns CC, Konz J, Wahid R, Gast C. Van Damme P, et al. Lancet. 2019 Jul 13;394(10193):148-158. doi: 10.1016/S0140-6736(19)31279-6. Epub 2019 Jun 4. Lancet. 2019. PMID: 31174831 Free PMC article. Clinical Trial.
64 results