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Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals.
Cruz-González S, Gu E, Gomez L, Mews M, Vance JM, Cuccaro ML, Cornejo-Olivas MR, Feliciano-Astacio BE, Byrd GS, Haines JL, Pericak-Vance MA, Griswold AJ, Bush WS, Capra JA. Cruz-González S, et al. Among authors: bush ws. bioRxiv [Preprint]. 2024 Oct 18:2024.10.16.618588. doi: 10.1101/2024.10.16.618588. bioRxiv. 2024. PMID: 39464059 Free PMC article. Preprint.
Amyloid-β predominant Alzheimer's disease neuropathologic change.
Kovacs GG, Katsumata Y, Wu X, Aung KZ, Fardo DW, Forrest SL; Alzheimer's Disease Genetics Consortium; Nelson PT. Kovacs GG, et al. Brain. 2024 Oct 17:awae325. doi: 10.1093/brain/awae325. Online ahead of print. Brain. 2024. PMID: 39417691
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
NIAGADS: A Comprehensive National Data Repository for Alzheimer's Disease and Related Dementia Genetics and Genomics Research.
Kuzma A, Valladares O, Greenfest-Allen E, Nicaretta H, Kirsch M, Ren Y, Katanic Z, White H, Wilk A, Bass L, Brettschneider J, Carter L, Cifello J, Chuang WH, Clark K, Gangadharan P, Haut J, Ho PC, Horng W, Iqbal T, Jin Y, Keskinen P, Rose AL, Moon MK, Manuel J, Qu L, Robbins F, Saravanan N, Sha J, Tate S, Zhao Y; Alzheimer’s Disease Sequencing Project; Cantwell L, Gardner J, Chou SY, Tzeng JY, Bush W, Naj A, Kuksa P, Lee WP, Leung YY, Schellenberg G, Wang LS. Kuzma A, et al. medRxiv [Preprint]. 2024 Dec 7:2024.10.07.24315029. doi: 10.1101/2024.10.07.24315029. medRxiv. 2024. PMID: 39417134 Free PMC article. Preprint.
Alzheimer's Disease Sequencing Project Release 4 Whole Genome Sequencing Dataset.
Leung YY, Lee WP, Kuzma AB, Nicaretta H, Valladares O, Gangadharan P, Qu L, Zhao Y, Ren Y, Cheng PL, Kuksa PP, Wang H, White H, Katanic Z, Bass L, Saravanan N, Greenfest-Allen E, Kirsch M, Cantwell L, Iqbal T, Wheeler NR, Farrell JJ, Zhu C, Turner SL, Gunasekaran TI, Mena PR, Jin J, Carter L; Alzheimer’s Disease Sequencing Project; Zhang X, Vardarajan BN, Toga A, Cuccaro M, Hohman TJ, Bush WS, Naj AC, Martin E, Dalgard C, Kunkle BW, Farrer LA, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Wang LS. Leung YY, et al. Among authors: bush ws. medRxiv [Preprint]. 2024 Dec 6:2024.12.03.24317000. doi: 10.1101/2024.12.03.24317000. medRxiv. 2024. PMID: 39677464 Free PMC article. Preprint.
Diverse ancestry GWAS for advanced age-related macular degeneration in TOPMed-imputed and Ophthalmologically-confirmed 16,108 cases and 18,038 controls.
Gorski M, Grunin M, Herold JM, Fröhlich B, Behr M, Wheeler N, Bush WS, Song YE, Zhu X, Blanton SH, Pericak-Vance MA, Heid IM, Haines JL; International Age-related Macular Degeneration Genomics Consortium. Gorski M, et al. Among authors: bush ws. medRxiv [Preprint]. 2024 Nov 11:2024.11.08.24316962. doi: 10.1101/2024.11.08.24316962. medRxiv. 2024. PMID: 39606372 Free PMC article. Preprint.
Constructing phylogenetic trees for microbiome data analysis: A mini-review.
Liu R, Qiao X, Shi Y, Peterson CB, Bush WS, Cominelli F, Wang M, Zhang L. Liu R, et al. Among authors: bush ws. Comput Struct Biotechnol J. 2024 Oct 24;23:3859-3868. doi: 10.1016/j.csbj.2024.10.032. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39554614 Free PMC article. Review.
Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites.
Tong T, Zhu C, Farrell JJ, Khurshid Z; Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Neuroimaging Initiative; Martin ER, Pericak-Vance MA, Wang LS, Bush WS, Schellenberg GD, Haines JL, Qiu WQ, Lunetta KL, Farrer LA, Zhang X. Tong T, et al. Among authors: bush ws. Alzheimers Res Ther. 2024 Oct 23;16(1):234. doi: 10.1186/s13195-024-01601-w. Alzheimers Res Ther. 2024. PMID: 39444005 Free PMC article.
Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.
Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Kunkle BW, Naj A, Blue EE, Nusetor F, Wang D, Boerwinkle E, Bush WS, Zhang X, De Jager PL, Dupuis J, Farrer LA, Fornage M, Martin E, Pericak-Vance M, Seshadri S, Wijsman EM, Wang LS; Alzheimer's Disease Sequencing Project; Schellenberg GD, Destefano AL, Haines JL, Peloso GM. Lee WP, et al. Among authors: bush ws. Alzheimers Dement. 2024 Dec;20(12):8470-8483. doi: 10.1002/alz.14283. Epub 2024 Oct 20. Alzheimers Dement. 2024. PMID: 39428839 Free PMC article.
197 results