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Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression.
Mol Ther. 2024 Dec 4;32(12):4514-4523. doi: 10.1016/j.ymthe.2024.10.028. Epub 2024 Oct 28.
Mol Ther. 2024.
PMID: 39473179
Free PMC article.
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression.
Perriera R, Vitale E, Pibiri I, Carollo PS, Ricci D, Corrao F, Fiduccia I, Melfi R, Zizzo MG, Tutone M, Pace A, Lentini L.
Perriera R, et al.
Int J Mol Sci. 2023 Oct 11;24(20):15084. doi: 10.3390/ijms242015084.
Int J Mol Sci. 2023.
PMID: 37894764
Free PMC article.
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Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation.
Corrao F, Zizzo MG, Tutone M, Melfi R, Fiduccia I, Carollo PS, Leonardo AD, Caldara G, Perriera R, Pace A, Belmonte B, Sammataro S, Pibiri I, Lentini L.
Corrao F, et al. Among authors: perriera r.
Biomed Pharmacother. 2022 Dec;156:113886. doi: 10.1016/j.biopha.2022.113886. Epub 2022 Oct 18.
Biomed Pharmacother. 2022.
PMID: 36265311
Free article.
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Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs).
Tutone M, Pibiri I, Perriera R, Campofelice A, Culletta G, Melfi R, Pace A, Almerico AM, Lentini L.
Tutone M, et al. Among authors: perriera r.
ACS Med Chem Lett. 2020 Feb 18;11(5):747-753. doi: 10.1021/acsmedchemlett.9b00609. eCollection 2020 May 14.
ACS Med Chem Lett. 2020.
PMID: 32435380
Free PMC article.
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