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H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response.
Oberholtzer N, Chakraborty P, Kassir MF, Dressman J, Das S, Mills S, Comte-Walters S, Gooz M, Choi S, Parikh RY, Hedley Z, Vaena S, DeMass R, Scurti G, Romeo M, Gangaraju VK, Berto S, Hill E, Ball LE, Mehta AS, Maldonado EN, Nishimura MI, Ogretmen B, Mehrotra S. Oberholtzer N, et al. Among authors: vaena s. Sci Adv. 2024 Nov 15;10(46):eadp1152. doi: 10.1126/sciadv.adp1152. Epub 2024 Nov 15. Sci Adv. 2024. PMID: 39546607 Free PMC article.
Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexia.
Pryce BR, Oles A, Talbert EE, Romeo MJ, Vaena S, Sharma S, Spadafora V, Tolliver L, Mahvi DA, Morgan KA, Lancaster WP, Beal E, Koren N, Watts B, Overstreet M, Berto S, Subramanian S, Calisir K, Crawford A, Neelon B, Ostrowski MC, Zimmers TA, Tidball JG, Wang DJ, Guttridge DC. Pryce BR, et al. Among authors: vaena s. Cell Rep. 2024 Nov 26;43(11):114925. doi: 10.1016/j.celrep.2024.114925. Epub 2024 Oct 30. Cell Rep. 2024. PMID: 39475511 Free article.
MYC is Sufficient to Generate Mid-Life High-Grade Serous Ovarian and Uterine Serous Carcinomas in a p53-R270H Mouse Model.
Blackman A, Rees AC, Bowers RR, Jones CM, Vaena SG, Clark MA, Carter S, Villamor ED, Evans D, Emanuel AJ, Fullbright G, O'Malley MS, Carpenter RL, Long DT, Spruill LS, Romeo MJ, Orr BC, Helke KL, Delaney JR. Blackman A, et al. Among authors: vaena sg. Cancer Res Commun. 2024 Sep 1;4(9):2525-2538. doi: 10.1158/2767-9764.CRC-24-0144. Cancer Res Commun. 2024. PMID: 39225558 Free PMC article.
High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells.
Cochrane RW, Robino RA, Granger B, Allen E, Vaena S, Romeo MJ, de Cubas AA, Berto S, Ferreira LMR. Cochrane RW, et al. Among authors: vaena s. bioRxiv [Preprint]. 2024 Apr 1:2024.03.31.587467. doi: 10.1101/2024.03.31.587467. bioRxiv. 2024. Update in: Mol Ther Methods Clin Dev. 2024 Nov 18;32(4):101385. doi: 10.1016/j.omtm.2024.101385 PMID: 38617240 Free PMC article. Updated. Preprint.
MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model.
Blackman A, Rees AC, Bowers RR, Jones CM, Vaena SG, Clark MA, Carter S, Villamor ED, Evans D, Emanuel AJ, Fullbright G, Long DT, Spruill L, Romeo MJ, Helke KL, Delaney JR. Blackman A, et al. Among authors: vaena sg. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.576924. doi: 10.1101/2024.01.24.576924. bioRxiv. 2024. Update in: Cancer Res Commun. 2024 Sep 1;4(9):2525-2538. doi: 10.1158/2767-9764.CRC-24-0144 PMID: 38352443 Free PMC article. Updated. Preprint.
Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development.
Harvey AB, Wolters RA, Deepe RN, Tarolli HG, Drummond JR, Trouten A, Zandi A, Barth JL, Mukherjee R, Romeo MJ, Vaena SG, Tao G, Muise-Helmericks R, Ramos PS, Norris RA, Wessels A. Harvey AB, et al. Among authors: vaena sg. J Mol Cell Cardiol. 2024 Jan;186:16-30. doi: 10.1016/j.yjmcc.2023.11.002. Epub 2023 Nov 5. J Mol Cell Cardiol. 2024. PMID: 37935281 Free article.
Cellular and Molecular Mechanisms of MEK1 Inhibitor-Induced Cardiotoxicity.
Beck TC, Arhontoulis DC, Morningstar JE, Hyams N, Stoddard A, Springs K, Mukherjee R, Helke K, Guo L, Moore K, Gensemer C, Biggs R, Petrucci T, Kwon J, Stayer K, Koren N, Harvey A, Holman H, Dunne J, Fulmer D, Vohra A, Mai L, Dooley S, Weninger J, Vaena S, Romeo M, Muise-Helmericks RC, Mei Y, Norris RA. Beck TC, et al. Among authors: vaena s. JACC CardioOncol. 2022 Nov 15;4(4):535-548. doi: 10.1016/j.jaccao.2022.07.009. eCollection 2022 Nov. JACC CardioOncol. 2022. PMID: 36444237 Free PMC article.
17 results