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Tumour-intrinsic PDL1 signals regulate the Chk2 DNA damage response in cancer cells and mediate resistance to Chk1 inhibitors.
Murray CE, Kornepati AVR, Ontiveros C, Liao Y, de la Peña Avalos B, Rogers CM, Liu Z, Deng Y, Bai H, Kari S, Padron AS, Boyd JT, Reyes R, Clark CA, Svatek RS, Li R, Hu Y, Wang M, Conejo-Garcia JR, Byers LA, Ramkumar K, Sood AK, Lee JM, Burd CE, Vadlamudi RK, Gupta HB, Zhao W, Dray E, Sung P, Curiel TJ. Murray CE, et al. Among authors: li r. Mol Cancer. 2024 Oct 30;23(1):242. doi: 10.1186/s12943-024-02147-z. Mol Cancer. 2024. PMID: 39478560 Free PMC article.
R-loop functions in Brca1-associated mammary tumorigenesis.
Chiang HC, Qi L, Mitra P, Huang Y, Hu Y, Li R. Chiang HC, et al. Among authors: li r. Proc Natl Acad Sci U S A. 2024 Aug 13;121(33):e2403600121. doi: 10.1073/pnas.2403600121. Epub 2024 Aug 8. Proc Natl Acad Sci U S A. 2024. PMID: 39116124
Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer.
Alečković M, Li Z, Zhou N, Qiu X, Lulseged B, Foidart P, Huang XY, Garza K, Shu S, Kesten N, Li R, Lim K, Garrido-Castro AC, Guerriero JL, Qi J, Long HW, Polyak K. Alečković M, et al. Among authors: li z, li r. Mol Cancer Ther. 2023 Nov 1;22(11):1304-1318. doi: 10.1158/1535-7163.MCT-23-0303. Mol Cancer Ther. 2023. PMID: 37676980 Free PMC article.
BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
Wu B, Qi L, Chiang HC, Pan H, Zhang X, Greenbaum A, Stark E, Wang LJ, Chen Y, Haddad BR, Clagett D, Isaacs C, Elledge R, Horvath A, Hu Y, Li R. Wu B, et al. Among authors: li r. J Immunother Cancer. 2023 Feb;11(2):e005852. doi: 10.1136/jitc-2022-005852. J Immunother Cancer. 2023. PMID: 36731891 Free PMC article.
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer.
Duplaquet L, So K, Ying AW, Pal Choudhuri S, Li X, Xu GD, Li Y, Qiu X, Li R, Singh S, Wu XS, Hamilton S, Chien VD, Liu Q, Qi J, Somerville TDD, Heiling HM, Mazzola E, Lee Y, Zoller T, Vakoc CR, Doench JG, Forrester WC, Abrams T, Long HW, Niederst MJ, Drapkin BJ, Kadoch C, Oser MG. Duplaquet L, et al. Among authors: li y, li x, li r. Cancer Cell. 2024 Aug 12;42(8):1352-1369.e13. doi: 10.1016/j.ccell.2024.06.012. Epub 2024 Jul 18. Cancer Cell. 2024. PMID: 39029464 Free article.
Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
Goyette MA, Stevens LE, DePinho CR, Seehawer M, Nishida J, Li Z, Wilde CM, Li R, Qiu X, Pyke AL, Zhao S, Lim K, Tender GS, Northey JJ, Riley NM, Long HW, Bertozzi CR, Weaver VM, Polyak K. Goyette MA, et al. Among authors: li z, li r. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2322688121. doi: 10.1073/pnas.2322688121. Epub 2024 May 6. Proc Natl Acad Sci U S A. 2024. PMID: 38709925 Free PMC article.
Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop.
Clifton GT, Rothenberg M, Ascierto PA, Begley G, Cecchini M, Eder JP, Ghiringhelli F, Italiano A, Kochetkova M, Li R, Mechta-Grigoriou F, Pai SI, Provenzano P, Puré E, Ribas A, Schalper KA, Fridman WH. Clifton GT, et al. Among authors: li r. J Immunother Cancer. 2023 Jun;11(6):e006773. doi: 10.1136/jitc-2023-006773. J Immunother Cancer. 2023. PMID: 37290925 Free PMC article.
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