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Endothelial cell-specific progerin expression does not cause cardiovascular alterations and premature death.
Benedicto I, Hamczyk MR, Nevado RM, Barettino A, Carmona RM, Espinós-Estévez C, Gonzalo P, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Dorado B, Andrés V. Benedicto I, et al. Among authors: gonzalez gomez c. Aging Cell. 2024 Oct 31:e14389. doi: 10.1111/acel.14389. Online ahead of print. Aging Cell. 2024. PMID: 39479939 Free article.
Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells.
Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V. Benedicto I, et al. Among authors: gonzalez gomez c. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2400752121. doi: 10.1073/pnas.2400752121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648484 Free PMC article.
Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome.
Dorado B, Pløen GG, Barettino A, Macías A, Gonzalo P, Andrés-Manzano MJ, González-Gómez C, Galán-Arriola C, Alfonso JM, Lobo M, López-Martín GJ, Molina A, Sánchez-Sánchez R, Gadea J, Sánchez-González J, Liu Y, Callesen H, Filgueiras-Rama D, Ibáñez B, Sørensen CB, Andrés V. Dorado B, et al. Cell Discov. 2019 Mar 19;5:16. doi: 10.1038/s41421-019-0084-z. eCollection 2019. Cell Discov. 2019. PMID: 30911407 Free PMC article.
Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.
Sánchez-López A, Espinós-Estévez C, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Fanjul V, Riquelme-Borja R, Hamczyk MR, Macías Á, Del Campo L, Camafeita E, Vázquez J, Barkaway A, Rolas L, Nourshargh S, Dorado B, Benedicto I, Andrés V. Sánchez-López A, et al. Circulation. 2021 Nov 30;144(22):1777-1794. doi: 10.1161/CIRCULATIONAHA.121.055313. Epub 2021 Oct 25. Circulation. 2021. PMID: 34694158 Free PMC article.
Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome.
Barettino A, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Guerrero CR, Espinosa FM, Carmona RM, Blanco Y, Dorado B, Torroja C, Sánchez-Cabo F, Quintas A, Benguría A, Dopazo A, García R, Benedicto I, Andrés V. Barettino A, et al. Among authors: gonzalez gomez c. J Clin Invest. 2024 Oct 1;134(22):e173448. doi: 10.1172/JCI173448. J Clin Invest. 2024. PMID: 39352768 Free PMC article.
Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite.
Del Campo L, Sánchez-López A, Salaices M, von Kleeck RA, Expósito E, González-Gómez C, Cussó L, Guzmán-Martínez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andrés V. Del Campo L, et al. Aging Cell. 2019 Jun;18(3):e12936. doi: 10.1111/acel.12936. Epub 2019 Mar 18. Aging Cell. 2019. PMID: 30884114 Free PMC article.
Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.
Macías Á, Díaz-Larrosa JJ, Blanco Y, Fanjul V, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, da Rocha AM, Ponce-Balbuena D, Allan A, Filgueiras-Rama D, Jalife J, Andrés V. Macías Á, et al. Cardiovasc Res. 2022 Jan 29;118(2):503-516. doi: 10.1093/cvr/cvab055. Cardiovasc Res. 2022. PMID: 33624748 Free PMC article.
80 results