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CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.
Jin Y, Basu S, Feng M, Ning Y, Munasinghe I, Joachim AM, Li J, Qin L, Madden R, Burks H, Gao P, Wu JQ, Sheikh SW, Joice AC, Perera C, Werbovetz KA, Zhang K, Wang MZ. Jin Y, et al. Among authors: sheikh sw. Nat Commun. 2024 Oct 31;15(1):9409. doi: 10.1038/s41467-024-53790-5. Nat Commun. 2024. PMID: 39482311 Free PMC article.