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Page 1
Arc mediates intercellular tau transmission via extracellular vesicles.
Tyagi M, Chadha R, de Hoog E, Sullivan KR, Walker AC, Northrop A, Fabian B, Fuxreiter M, Hyman BT, Shepherd JD. Tyagi M, et al. Among authors: hyman bt. bioRxiv [Preprint]. 2024 Oct 22:2024.10.22.619703. doi: 10.1101/2024.10.22.619703. bioRxiv. 2024. PMID: 39484489 Free PMC article. Preprint.
Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau.
Mate de Gerando A, Welikovitch LA, Khasnavis A, Commins C, Glynn C, Chun JE, Perbet R, Hyman BT. Mate de Gerando A, et al. Among authors: hyman bt. bioRxiv [Preprint]. 2023 May 26:2023.03.28.534418. doi: 10.1101/2023.03.28.534418. bioRxiv. 2023. Update in: Acta Neuropathol. 2023 Aug;146(2):191-210. doi: 10.1007/s00401-023-02600-1 PMID: 37034629 Free PMC article. Updated. Preprint.
Brain Vasculature Accumulates Tau and Is Spatially Related to Tau Tangle Pathology in Alzheimer's Disease.
Hoglund Z, Ruiz-Uribe N, Del Sastre E, Woost B, Bailey J, Hyman BT, Zwang T, Bennett RE. Hoglund Z, et al. Among authors: hyman bt. bioRxiv [Preprint]. 2024 Jan 28:2024.01.27.577088. doi: 10.1101/2024.01.27.577088. bioRxiv. 2024. Update in: Acta Neuropathol. 2024 Jun 17;147(1):101. doi: 10.1007/s00401-024-02751-9 PMID: 38328111 Free PMC article. Updated. Preprint.
The big tau splice isoform resists Alzheimer's-related pathological changes.
Chung DC, Deng X, Yalamanchili HK, Revelli JP, Han AL, Tadros B, Richman R, Dias M, Naini FA, Boeynaems S, Hyman BT, Zoghbi HY. Chung DC, et al. Among authors: hyman bt. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605685. doi: 10.1101/2024.07.30.605685. bioRxiv. 2024. PMID: 39211086 Free PMC article. Preprint.
Molecular Polymorphism of tau aggregates in Pick's disease.
Liu J, Stewart TC, Hyman BT, Burghammer M, Cotte M, Makowski L. Liu J, et al. Among authors: hyman bt. bioRxiv [Preprint]. 2024 Nov 19:2024.11.19.624253. doi: 10.1101/2024.11.19.624253. bioRxiv. 2024. PMID: 39605720 Free PMC article. Preprint.
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer's disease.
Serrano-Pozo A, Li H, Li Z, Muñoz-Castro C, Jaisa-Aad M, Healey MA, Welikovitch LA, Jayakumar R, Bryant AG, Noori A, Connors TR, Hu M, Zhao K, Liao F, Lin G, Pastika T, Tamm J, Abdourahman A, Kwon T, Bennett RE, Woodbury ME, Wachter A, Talanian RV, Biber K, Karran EH, Hyman BT, Das S. Serrano-Pozo A, et al. Among authors: hyman bt. Nat Neurosci. 2024 Dec;27(12):2384-2400. doi: 10.1038/s41593-024-01791-4. Epub 2024 Nov 11. Nat Neurosci. 2024. PMID: 39528672 Free PMC article.
X-chromosome-wide association study for Alzheimer's disease.
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S; EADB, GR@ACE, DEGESCO, EADI, GERAD, DemGene, FinnGen, ADGC, CHARGE; Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-… See abstract for full author list ➔ Le Borgne J, et al. Mol Psychiatry. 2024 Dec 4. doi: 10.1038/s41380-024-02838-5. Online ahead of print. Mol Psychiatry. 2024. PMID: 39633006
Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology.
Gazula H, Tregidgo HFJ, Billot B, Balbastre Y, William-Ramirez J, Herisse R, Deden-Binder LJ, Casamitjana A, Melief EJ, Latimer CS, Kilgore MD, Montine M, Robinson E, Blackburn E, Marshall MS, Connors TR, Oakley DH, Frosch MP, Young SI, Van Leemput K, Dalca AV, FIschl B, Mac Donald CL, Keene CD, Hyman BT, Iglesias JE. Gazula H, et al. Among authors: hyman bt. bioRxiv [Preprint]. 2024 Jan 30:2023.06.08.544050. doi: 10.1101/2023.06.08.544050. bioRxiv. 2024. Update in: Elife. 2024 Jun 19;12:RP91398. doi: 10.7554/eLife.91398 PMID: 37333251 Free PMC article. Updated. Preprint.
830 results