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A weight of evidence review on the mode of action, adversity, and the human relevance of xylene's observed thyroid effects in rats.
Morris-Schaffer K, Higgins L, Kocabas NA, Faulhammer F, Cordova A, Freeman E, Kamp H, Nahar M, Richmond E, Rooseboom M. Morris-Schaffer K, et al. Among authors: higgins l. Crit Rev Toxicol. 2025 Jan 9:1-26. doi: 10.1080/10408444.2024.2422890. Online ahead of print. Crit Rev Toxicol. 2025. PMID: 39785829 Free article. Review.
Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs.
Kazmirczak F, Moon R, Vogel NT, Tollison W, Lahti MT, Carney JP, Mendelson JB, Markowski T, Higgins L, Murray K, Guerrero C, Prins KW. Kazmirczak F, et al. Among authors: higgins l. Am J Respir Crit Care Med. 2024 Dec 19. doi: 10.1164/rccm.202406-1197RL. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39700526 No abstract available.
Impact of the Smarter Safer Homes Solution on Quality of Life and Health Outcomes in Older People Living in Their Own Homes: Randomized Controlled Trial.
Lu W, Silvera-Tawil D, Yoon HJ, Higgins L, Zhang Q, Karunanithi M, Bomke J, Byrnes J, Hewitt J, Smallbon V, Freyne J, Prabhu D, Varnfield M. Lu W, et al. Among authors: higgins l. J Med Internet Res. 2024 Nov 11. doi: 10.2196/59921. Online ahead of print. J Med Internet Res. 2024. PMID: 39608020 Free article.
Xylene: weight of evidence approach case study to determine the need for an extended one generation reproductive study with a developmental neurotoxicity animal cohort.
Faulhammer F, Rooseboom M, Kocabas NA, Arts JHE, Cordova A, Freeman E, Higgins LG, Nahar M, Richmond E, Schneider S, Morris-Schaffer K. Faulhammer F, et al. Among authors: higgins lg. Crit Rev Toxicol. 2024 Nov;54(10):925-952. doi: 10.1080/10408444.2024.2413073. Epub 2024 Nov 12. Crit Rev Toxicol. 2024. PMID: 39530411 Free article. Review.
Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin.
Lemmex ACD, Allred J, Ostergard J, Trask J, Bui HN, Anderson MJM, Kopp B, Streeter O, Smiley AT, Babilonia-Díaz NS, Blazar BR, Higgins L, Gordon PM, Muretta JM, Gordon WR. Lemmex ACD, et al. Among authors: higgins l. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.617501. doi: 10.1101/2024.10.22.617501. bioRxiv. 2024. PMID: 39484510 Free PMC article. Preprint.
Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs.
Kazmirczak F, Moon R, Vogel NT, Tollison W, T Lahti M, Carney JP, Mendelson JB, Markowski T, Higgins L, Murray K, Guerrero C, Prins KW. Kazmirczak F, et al. Among authors: higgins l. bioRxiv [Preprint]. 2024 Oct 24:2024.04.24.590907. doi: 10.1101/2024.04.24.590907. bioRxiv. 2024. Update in: Am J Respir Crit Care Med. 2024 Dec 19. doi: 10.1164/rccm.202406-1197RL PMID: 39484509 Free PMC article. Updated. Preprint.
Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension.
Kazmirczak F, Vogel NT, Prisco SZ, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Calixto Mancipe N, Markowski T, Higgins L, Guerrero C, Kremer B, Blake ML, Rhodes CJ, Williams JW, Brittain EL, Prins KW. Kazmirczak F, et al. Among authors: higgins l. Circ Res. 2024 Nov 8;135(11):1067-1083. doi: 10.1161/CIRCRESAHA.123.324138. Epub 2024 Oct 18. Circ Res. 2024. PMID: 39421926 Free article.
Editorial Expression of Concern: p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells.
Hideshima T, Podar K, Chauhan D, Ishitsuka K, Mitsiades C, Tai YT, Hamasaki M, Raje N, Hideshima H, Schreiner G, Nguyen AN, Navas T, Munshi NC, Richardson PG, Higgins LS, Anderson KC. Hideshima T, et al. Among authors: higgins ls. Oncogene. 2024 Sep;43(40):3018. doi: 10.1038/s41388-024-03147-5. Oncogene. 2024. PMID: 39209967 No abstract available.
733 results