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110 results

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Page 1
WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer.
Citron F, Ho IL, Balestrieri C, Liu Z, Yen EY, Cecchetto L, Perelli L, Zhang L, Montanez LC, Blazanin N, Dyke CA, Shah R, Attanasio S, Srinivasan S, Chen KC, Chen Z, Scognamiglio I, Pham N, Khan H, Jiang S, Pan J, Vanderkruk B, Leung CS, Mattohti M, Rai K, Chu Y, Wang L, Gao S, Deem AK, Carugo A, Wang H, Yao W, Tonon G, Xiong Y, Lorenzi PL, Bonini C, Anna Zal M, Hoffman BG, Heffernan T, Giuliani V, Jeter CR, Lissanu Y, Genovese G, Pilato MD, Viale A, Draetta GF. Citron F, et al. Among authors: balestrieri c. bioRxiv [Preprint]. 2024 Oct 24:2024.10.21.619543. doi: 10.1101/2024.10.21.619543. bioRxiv. 2024. PMID: 39484624 Free PMC article. Preprint.
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.
Del Poggetto E, Ho IL, Balestrieri C, Yen EY, Zhang S, Citron F, Shah R, Corti D, Diaferia GR, Li CY, Loponte S, Carbone F, Hayakawa Y, Valenti G, Jiang S, Sapio L, Jiang H, Dey P, Gao S, Deem AK, Rose-John S, Yao W, Ying H, Rhim AD, Genovese G, Heffernan TP, Maitra A, Wang TC, Wang L, Draetta GF, Carugo A, Natoli G, Viale A. Del Poggetto E, et al. Among authors: balestrieri c. Science. 2021 Sep 17;373(6561):eabj0486. doi: 10.1126/science.abj0486. Epub 2021 Sep 17. Science. 2021. PMID: 34529467 Free PMC article.
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells.
Punzi S, Balestrieri C, D'Alesio C, Bossi D, Dellino GI, Gatti E, Pruneri G, Criscitiello C, Lovati G, Meliksetyan M, Carugo A, Curigliano G, Natoli G, Pelicci PG, Lanfrancone L. Punzi S, et al. Among authors: balestrieri c. Breast Cancer Res. 2019 Nov 21;21(1):123. doi: 10.1186/s13058-019-1216-y. Breast Cancer Res. 2019. PMID: 31752957 Free PMC article.
Harnessing T cell exhaustion and trogocytosis to isolate patient-derived tumor-specific TCR.
Manfredi F, Stasi L, Buonanno S, Marzuttini F, Noviello M, Mastaglio S, Abbati D, Potenza A, Balestrieri C, Cianciotti BC, Tassi E, Feola S, Toffalori C, Punta M, Magnani Z, Camisa B, Tiziano E, Lupo-Stanghellini MT, Branca RM, Lehtiö J, Sikanen TM, Haapala MJ, Cerullo V, Casucci M, Vago L, Ciceri F, Bonini C, Ruggiero E. Manfredi F, et al. Among authors: balestrieri c. Sci Adv. 2023 Dec;9(48):eadg8014. doi: 10.1126/sciadv.adg8014. Epub 2023 Dec 1. Sci Adv. 2023. PMID: 38039364 Free PMC article.
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells.
Manfredi F, Abbati D, Cianciotti BC, Stasi L, Potenza A, Ruggiero E, Magnani Z, Carnevale E, Doglio M, Noviello M, Tassi E, Balestrieri C, Buonanno S, Clemente F, De Lalla C, Protti MP, Mondino A, Casorati G, Dellabona P, Bonini C. Manfredi F, et al. Among authors: balestrieri c. Eur J Immunol. 2021 Aug;51(8):1992-2005. doi: 10.1002/eji.202049103. Epub 2021 Jun 21. Eur J Immunol. 2021. PMID: 34081326 Free article.
Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells.
Tassi E, Bergamini A, Wignall J, Sant'Angelo M, Brunetto E, Balestrieri C, Redegalli M, Potenza A, Abbati D, Manfredi F, Cangi MG, Magliacane G, Scalisi F, Ruggiero E, Maffia MC, Trippitelli F, Rabaiotti E, Cioffi R, Bocciolone L, Candotti G, Candiani M, Taccagni G, Schultes B, Doglioni C, Mangili G, Bonini C. Tassi E, et al. Among authors: balestrieri c. Front Immunol. 2023 Oct 4;14:1212444. doi: 10.3389/fimmu.2023.1212444. eCollection 2023. Front Immunol. 2023. PMID: 37868997 Free PMC article.
In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases.
Kerzel T, Giacca G, Beretta S, Bresesti C, Notaro M, Scotti GM, Balestrieri C, Canu T, Redegalli M, Pedica F, Genua M, Ostuni R, Kajaste-Rudnitski A, Oshima M, Tonon G, Merelli I, Aldrighetti L, Dellabona P, Coltella N, Doglioni C, Rancoita PMV, Sanvito F, Naldini L, Squadrito ML. Kerzel T, et al. Among authors: balestrieri c. Cancer Cell. 2023 Nov 13;41(11):1892-1910.e10. doi: 10.1016/j.ccell.2023.09.014. Epub 2023 Oct 19. Cancer Cell. 2023. PMID: 37863068 Free article.
Pro-tumor Tfh2 cells induce detrimental IgG4 production and PGE2-dependent IgE inhibition in pancreatic cancer.
De Monte L, Clemente F, Ruggiero E, Pini R, Ceraolo MG, Schiavo Lena M, Balestrieri C, Lazarevic D, Belfiori G, Crippa S, Balzano G, Falconi M, Doglioni C, Bonini C, Reni M, Protti MP. De Monte L, et al. Among authors: balestrieri c. EBioMedicine. 2023 Nov;97:104819. doi: 10.1016/j.ebiom.2023.104819. Epub 2023 Sep 28. EBioMedicine. 2023. PMID: 37776595 Free PMC article.
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells.
Potenza A, Balestrieri C, Spiga M, Albarello L, Pedica F, Manfredi F, Cianciotti BC, De Lalla C, Botrugno OA, Faccani C, Stasi L, Tassi E, Bonfiglio S, Scotti GM, Redegalli M, Biancolini D, Camisa B, Tiziano E, Sirini C, Casucci M, Iozzi C, Abbati D, Simeoni F, Lazarevic D, Elmore U, Fiorentini G, Di Lullo G, Casorati G, Doglioni C, Tonon G, Dellabona P, Rosati R, Aldrighetti L, Ruggiero E, Bonini C. Potenza A, et al. Among authors: balestrieri c. Gut. 2023 Oct;72(10):1887-1903. doi: 10.1136/gutjnl-2022-328042. Epub 2023 Jun 30. Gut. 2023. PMID: 37399271
110 results