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Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinoma.
Tu Y, Wu H, Zhong C, Liu Y, Xiong Z, Chen S, Wang J, Wong PP, Yang W, Liang Z, Lu J, Chen S, Zhang L, Feng Y, Si-Tou WW, Yin B, Lin Y, Liang J, Liang L, Vong JSL, Ren W, Kwong TT, Leung H, To KF, Ma S, Tong M, Sun H, Xia Q, Zhou J, Kerr D, La Thangue N, Sung JJY, Chan SL, Cheng AS. Tu Y, et al. Among authors: chan sl. Gut. 2024 Nov 1:gutjnl-2024-332281. doi: 10.1136/gutjnl-2024-332281. Online ahead of print. Gut. 2024. PMID: 39486886 Free article.
Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma.
Liu M, Zhou J, Liu X, Feng Y, Yang W, Wu F, Cheung OK, Sun H, Zeng X, Tang W, Mok MTS, Wong J, Yeung PC, Lai PBS, Chen Z, Jin H, Chen J, Chan SL, Chan AWH, To KF, Sung JJY, Chen M, Cheng AS. Liu M, et al. Among authors: chan awh, chan sl. Gut. 2020 Feb;69(2):365-379. doi: 10.1136/gutjnl-2018-317257. Epub 2019 May 10. Gut. 2020. PMID: 31076403
Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis.
Zeng X, Zhou J, Xiong Z, Sun H, Yang W, Mok MTS, Wang J, Li J, Liu M, Tang W, Feng Y, Wang HK, Tsang SW, Chow KL, Yeung PC, Wong J, Lai PB, Chan AW, To KF, Chan SL, Xia Q, Xue J, Chen X, Yu J, Peng S, Sung JJ, Kuang M, Cheng AS. Zeng X, et al. Among authors: chan sl, chan aw. Cell Mol Immunol. 2021 Apr;18(4):1005-1015. doi: 10.1038/s41423-020-00534-2. Epub 2020 Sep 2. Cell Mol Immunol. 2021. PMID: 32879468 Free PMC article.
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma.
Yang W, Feng Y, Zhou J, Cheung OK, Cao J, Wang J, Tang W, Tu Y, Xu L, Wu F, Tan Z, Sun H, Tian Y, Wong J, Lai PB, Chan SL, Chan AW, Tan PB, Chen Z, Sung JJ, Yip KY, To KF, Cheng AS. Yang W, et al. Among authors: chan sl, chan aw. Sci Transl Med. 2021 Apr 7;13(588):eaaz6804. doi: 10.1126/scitranslmed.aaz6804. Sci Transl Med. 2021. PMID: 33827976
698 results