Walker LSK - Search Results

1

An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy.

Jamison BL, Lawrance M, Wang CJ, DeBerg HA, Ziegler LJ, Sansom DM, Gavin MA, Walker LSK, Campbell DJ. Jamison BL, et al. Among authors: walker lsk. Cell Rep. 2024 Nov 26;43(11):114938. doi: 10.1016/j.celrep.2024.114938. Epub 2024 Nov 2. Cell Rep. 2024. PMID: 39488830 Free PMC article.

2

An IL-2 mutein increases IL-10 and CTLA-4-dependent suppression of dendritic cells by regulatory T cells.

Jamison BL, Lawrance M, Wang CJ, DeBerg HA, Sansom DM, Gavin MA, Walker LSK, Campbell DJ. Jamison BL, et al. Among authors: walker lsk. bioRxiv [Preprint]. 2023 Dec 4:2023.12.01.569613. doi: 10.1101/2023.12.01.569613. bioRxiv. 2023. Update in: Cell Rep. 2024 Nov 26;43(11):114938. doi: 10.1016/j.celrep.2024.114938 PMID: 38106196 Free PMC article. Updated. Preprint.

3

Confusing signals: recent progress in CTLA-4 biology.

Walker LS, Sansom DM. Walker LS, et al. Trends Immunol. 2015 Feb;36(2):63-70. doi: 10.1016/j.it.2014.12.001. Epub 2015 Jan 9. Trends Immunol. 2015. PMID: 25582039 Free PMC article. Review.

4

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells.

Hou TZ, Qureshi OS, Wang CJ, Baker J, Young SP, Walker LS, Sansom DM. Hou TZ, et al. J Immunol. 2015 Mar 1;194(5):2148-59. doi: 10.4049/jimmunol.1401876. Epub 2015 Jan 28. J Immunol. 2015. PMID: 25632005 Free PMC article.

5

CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells.

Ovcinnikovs V, Ross EM, Petersone L, Edner NM, Heuts F, Ntavli E, Kogimtzis A, Kennedy A, Wang CJ, Bennett CL, Sansom DM, Walker LSK. Ovcinnikovs V, et al. Among authors: walker lsk. Sci Immunol. 2019 May 31;4(35):eaaw0902. doi: 10.1126/sciimmunol.aaw0902. Sci Immunol. 2019. PMID: 31152091 Free PMC article.

6

Dimers Aren't Forever: CD80 Breaks up with PD-L1.

Sansom DM, Walker LSK. Sansom DM, et al. Among authors: walker lsk. Immunity. 2019 Dec 17;51(6):972-974. doi: 10.1016/j.immuni.2019.11.011. Immunity. 2019. PMID: 31951541 Free article.

7

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology.

Sansom DM, Walker LS. Sansom DM, et al. Immunol Rev. 2006 Aug;212:131-48. doi: 10.1111/j.0105-2896.2006.00419.x. Immunol Rev. 2006. PMID: 16903911 Review.

8

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

Jeffery LE, Burke F, Mura M, Zheng Y, Qureshi OS, Hewison M, Walker LS, Lammas DA, Raza K, Sansom DM. Jeffery LE, et al. J Immunol. 2009 Nov 1;183(9):5458-67. doi: 10.4049/jimmunol.0803217. J Immunol. 2009. PMID: 19843932 Free PMC article.

9

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement.

Wang CJ, Heuts F, Ovcinnikovs V, Wardzinski L, Bowers C, Schmidt EM, Kogimtzis A, Kenefeck R, Sansom DM, Walker LS. Wang CJ, et al. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):524-9. doi: 10.1073/pnas.1414576112. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548162 Free PMC article.

10

Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations.

Verma N, Burns SO, Walker LSK, Sansom DM. Verma N, et al. Among authors: walker lsk. Clin Exp Immunol. 2017 Oct;190(1):1-7. doi: 10.1111/cei.12997. Epub 2017 Jul 21. Clin Exp Immunol. 2017. PMID: 28600865 Free PMC article. Review.

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