Gomez-Soler M - Search Results

1

Lipidation and PEGylation strategies to prolong the in vivo half-life of a nanomolar EphA4 receptor antagonist.

Gomez-Soler M, Olson EJ, Rubio de la Torre E, Zhao C, Lamberto I, Flood DT, Danho W, Lechtenberg BC, Riedl SJ, Dawson PE, Pasquale EB. Gomez-Soler M, et al. Eur J Med Chem. 2023 Oct 16;262:115876. doi: 10.1016/j.ejmech.2023.115876. Online ahead of print. Eur J Med Chem. 2023. PMID: 39491430

2

Lipidation and PEGylation Strategies to Prolong the in Vivo Half-Life of a Nanomolar EphA4 Receptor Antagonist.

Gomez-Soler M, Olson EJ, de la Torre ER, Zhao C, Lamberto I, Flood DT, Danho W, Lechtenberg BC, Riedl SJ, Dawson PE, Pasquale EB. Gomez-Soler M, et al. Eur J Med Chem. 2023 Dec 15;262:115876. doi: 10.1016/j.ejmech.2023.115876. Epub 2023 Oct 16. Eur J Med Chem. 2023. PMID: 38523699 Free PMC article.

3

Missense mutations of the ephrin receptor EPHA1 associated with Alzheimer's disease disrupt receptor signaling functions.

Matsumoto M, Gomez-Soler M, Lombardi S, Lechtenberg BC, Pasquale EB. Matsumoto M, et al. Among authors: gomez soler m. J Biol Chem. 2024 Dec 18;301(2):108099. doi: 10.1016/j.jbc.2024.108099. Online ahead of print. J Biol Chem. 2024. PMID: 39706267 Free article.

4

Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling.

Gomez-Soler M, Gehring MP, Lechtenberg BC, Zapata-Mercado E, Ruelos A, Matsumoto MW, Hristova K, Pasquale EB. Gomez-Soler M, et al. iScience. 2022 Feb 4;25(3):103870. doi: 10.1016/j.isci.2022.103870. eCollection 2022 Mar 18. iScience. 2022. PMID: 35243233 Free PMC article.

5

A cancer mutation promotes EphA4 oligomerization and signaling by altering the conformation of the SAM domain.

Light TP, Gomez-Soler M, Wang Z, Karl K, Zapata-Mercado E, Gehring MP, Lechtenberg BC, Pogorelov TV, Hristova K, Pasquale EB. Light TP, et al. Among authors: gomez soler m. J Biol Chem. 2021 Jul;297(1):100876. doi: 10.1016/j.jbc.2021.100876. Epub 2021 Jun 15. J Biol Chem. 2021. PMID: 34139238 Free PMC article.

6

Environmental enrichment during the chronic phase after experimental stroke promotes functional recovery without synergistic effects of EphA4 targeted therapy.

de Boer A, Storm A, Gomez-Soler M, Smolders S, Rué L, Poppe L, B Pasquale E, Robberecht W, Lemmens R. de Boer A, et al. Among authors: gomez soler m. Hum Mol Genet. 2020 Mar 13;29(4):605-617. doi: 10.1093/hmg/ddz288. Hum Mol Genet. 2020. PMID: 31814004 Free PMC article.

7

Revealing Adenosine A_2A-Dopamine D₂ Receptor Heteromers in Parkinson's Disease Post-Mortem Brain through a New AlphaScreen-Based Assay.

Fernández-Dueñas V, Gómez-Soler M, Valle-León M, Watanabe M, Ferrer I, Ciruela F. Fernández-Dueñas V, et al. Among authors: gomez soler m. Int J Mol Sci. 2019 Jul 23;20(14):3600. doi: 10.3390/ijms20143600. Int J Mol Sci. 2019. PMID: 31340557 Free PMC article.

8

Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.

Gomez-Soler M, Petersen Gehring M, Lechtenberg BC, Zapata-Mercado E, Hristova K, Pasquale EB. Gomez-Soler M, et al. J Biol Chem. 2019 May 31;294(22):8791-8805. doi: 10.1074/jbc.RA119.008213. Epub 2019 Apr 23. J Biol Chem. 2019. PMID: 31015204 Free PMC article.

9

Triglyceride Form of Docosahexaenoic Acid Mediates Neuroprotection in Experimental Parkinsonism.

Gómez-Soler M, Cordobilla B, Morató X, Fernández-Dueñas V, Domingo JC, Ciruela F. Gómez-Soler M, et al. Front Neurosci. 2018 Aug 28;12:604. doi: 10.3389/fnins.2018.00604. eCollection 2018. Front Neurosci. 2018. PMID: 30233293 Free PMC article.

10

Antipsychotic-Like Efficacy of Dopamine D₂ Receptor-Biased Ligands is Dependent on Adenosine A_2A Receptor Expression.

Sahlholm K, Gómez-Soler M, Valle-León M, López-Cano M, Taura JJ, Ciruela F, Fernández-Dueñas V. Sahlholm K, et al. Among authors: gomez soler m. Mol Neurobiol. 2018 Jun;55(6):4952-4958. doi: 10.1007/s12035-017-0696-y. Epub 2017 Aug 5. Mol Neurobiol. 2018. PMID: 28779351

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