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PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity.
Gilglioni EH, Li A, St-Pierre-Wijckmans W, Shen TK, Pérez-Chávez I, Hovhannisyan G, Lisjak M, Negueruela J, Vandenbempt V, Bauzá-Martinez J, Herranz JM, Ezeriņa D, Demine S, Feng Z, Vignane T, Otero Sanchez L, Lambertucci F, Prašnická A, Devière J, Hay DC, Encinar JA, Singh SP, Messens J, Filipovic MR, Sharpe HJ, Trépo E, Wu W, Gurzov EN. Gilglioni EH, et al. Among authors: demine s. Nat Commun. 2024 Nov 4;15(1):9522. doi: 10.1038/s41467-024-53733-0. Nat Commun. 2024. PMID: 39496584 Free PMC article.
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice.
Syed F, Ballew O, Lee CC, Rana J, Krishnan P, Castela A, Weaver SA, Chalasani NS, Thomaidou SF, Demine S, Chang G, Coomans de Brachène A, Alvelos MI, Marselli L, Orr K, Felton JL, Liu J, Marchetti P, Zaldumbide A, Scheuner D, Eizirik DL, Evans-Molina C. Syed F, et al. Among authors: demine s. bioRxiv [Preprint]. 2024 May 9:2024.03.20.585925. doi: 10.1101/2024.03.20.585925. bioRxiv. 2024. PMID: 38766166 Free PMC article. Preprint.
HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes.
Vandenbempt V, Eski SE, Brahma MK, Li A, Negueruela J, Bruggeman Y, Demine S, Xiao P, Cardozo AK, Baeyens N, Martelotto LG, Singh SP, Mariño E, Gysemans C, Gurzov EN. Vandenbempt V, et al. Among authors: demine s. iScience. 2023 Dec 10;27(1):108694. doi: 10.1016/j.isci.2023.108694. eCollection 2024 Jan 19. iScience. 2023. PMID: 38213620 Free PMC article.
Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
Cosentino C, Toivonen S, Diaz Villamil E, Atta M, Ravanat JL, Demine S, Schiavo AA, Pachera N, Deglasse JP, Jonas JC, Balboa D, Otonkoski T, Pearson ER, Marchetti P, Eizirik DL, Cnop M, Igoillo-Esteve M. Cosentino C, et al. Among authors: demine s. Nucleic Acids Res. 2018 Nov 2;46(19):10302-10318. doi: 10.1093/nar/gky839. Nucleic Acids Res. 2018. PMID: 30247717 Free PMC article.
18 results