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Looking back at the TEDDY study: lessons and future directions.
Lernmark Å, Agardh D, Akolkar B, Gesualdo P, Hagopian WA, Haller MJ, Hyöty H, Johnson SB, Elding Larsson H, Liu E, Lynch KF, McKinney EF, McIndoe R, Melin J, Norris JM, Rewers M, Rich SS, Toppari J, Triplett E, Vehik K, Virtanen SM, Ziegler AG, Schatz DA, Krischer J. Lernmark Å, et al. Among authors: triplett e. Nat Rev Endocrinol. 2024 Nov 4. doi: 10.1038/s41574-024-01045-0. Online ahead of print. Nat Rev Endocrinol. 2024. PMID: 39496810 Review.
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, Akolkar B, Schatz DA, Atkinson MA, Triplett EW; TEDDY Study Group. Kemppainen KM, et al. Diabetes Care. 2015 Feb;38(2):329-32. doi: 10.2337/dc14-0850. Epub 2014 Dec 17. Diabetes Care. 2015. PMID: 25519450 Free PMC article.
Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life.
Kemppainen KM, Lynch KF, Liu E, Lönnrot M, Simell V, Briese T, Koletzko S, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Lernmark Å, Hyöty H, Triplett EW, Agardh D; TEDDY Study Group. Kemppainen KM, et al. Among authors: triplett ew. Clin Gastroenterol Hepatol. 2017 May;15(5):694-702.e5. doi: 10.1016/j.cgh.2016.10.033. Epub 2016 Nov 10. Clin Gastroenterol Hepatol. 2017. PMID: 27840181 Free PMC article.
Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.
Kemppainen KM, Vehik K, Lynch KF, Larsson HE, Canepa RJ, Simell V, Koletzko S, Liu E, Simell OG, Toppari J, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian WA, She JX, Akolkar B, Schatz DA, Atkinson MA, Blaser MJ, Krischer JP, Hyöty H, Agardh D, Triplett EW; Environmental Determinants of Diabetes in the Young (TEDDY) Study Group. Kemppainen KM, et al. Among authors: triplett ew. JAMA Pediatr. 2017 Dec 1;171(12):1217-1225. doi: 10.1001/jamapediatrics.2017.2905. JAMA Pediatr. 2017. PMID: 29052687 Free PMC article.
Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.
Törn C, Liu X, Onengut-Gumuscu S, Counts KM, Moreno JL, Remedios CL, Chen WM, LeFaive J, Butterworth MD, Akolkar B, Krischer JP, Lernmark Å, Rewers M, She JX, Toppari J, Ziegler AG, Ratan A, Smith AV, Hagopian WA, Rich SS, Parikh HM; TEDDY Study Group. Törn C, et al. Sci Rep. 2022 Mar 16;12(1):4516. doi: 10.1038/s41598-022-08058-7. Sci Rep. 2022. PMID: 35296692 Free PMC article.
242 results