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Corrigendum to Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists "Biomed. Pharmacother. 176 (2024) 116821".
Chvojkova M, Kolar D, Kovacova K, Cejkova L, Misiachna A, Hakenova K, Gorecki L, Horak M, Korabecny J, Soukup O, Vales K. Chvojkova M, et al. Among authors: vales k. Biomed Pharmacother. 2024 Dec;181:117660. doi: 10.1016/j.biopha.2024.117660. Epub 2024 Nov 4. Biomed Pharmacother. 2024. PMID: 39500698 Free article. No abstract available.
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
Gorecki L, Misiachna A, Damborsky J, Dolezal R, Korabecny J, Cejkova L, Hakenova K, Chvojkova M, Karasova JZ, Prchal L, Novak M, Kolcheva M, Kortus S, Vales K, Horak M, Soukup O. Gorecki L, et al. Among authors: vales k. Eur J Med Chem. 2021 Jul 5;219:113434. doi: 10.1016/j.ejmech.2021.113434. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33892271 Free article.
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.
Misiachna A, Svobodova B, Netolicky J, Chvojkova M, Kleteckova L, Prchal L, Novak M, Hrabinova M, Kucera T, Muckova L, Moravcova Z, Karasova JZ, Pejchal J, Blazek F, Malinak D, Hakenova K, Krausova BH, Kolcheva M, Ladislav M, Korabecny J, Pahnke J, Vales K, Horak M, Soukup O. Misiachna A, et al. Among authors: vales k. Eur J Med Chem. 2024 Feb 15;266:116130. doi: 10.1016/j.ejmech.2024.116130. Epub 2024 Jan 7. Eur J Med Chem. 2024. PMID: 38218127 Free article.
Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects.
Konecny J, Misiachna A, Chvojkova M, Kleteckova L, Kolcheva M, Novak M, Prchal L, Ladislav M, Hemelikova K, Netolicky J, Hrabinova M, Kobrlova T, Karasova JZ, Pejchal J, Fibigar J, Vecera Z, Kucera T, Jendelova P, Zahumenska P, Langore E, Doderovic J, Pang YP, Vales K, Korabecny J, Soukup O, Horak M. Konecny J, et al. Among authors: vales k. Eur J Med Chem. 2024 Dec 15;280:116981. doi: 10.1016/j.ejmech.2024.116981. Epub 2024 Oct 18. Eur J Med Chem. 2024. PMID: 39442339 Free article.
The pharmacology of tacrine at N-methyl-d-aspartate receptors.
Horak M, Holubova K, Nepovimova E, Krusek J, Kaniakova M, Korabecny J, Vyklicky L, Kuca K, Stuchlik A, Ricny J, Vales K, Soukup O. Horak M, et al. Among authors: vales k. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Apr 3;75:54-62. doi: 10.1016/j.pnpbp.2017.01.003. Epub 2017 Jan 13. Prog Neuropsychopharmacol Biol Psychiatry. 2017. PMID: 28089695 Review.
7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo.
Kaniakova M, Korabecny J, Holubova K, Kleteckova L, Chvojkova M, Hakenova K, Prchal L, Novak M, Dolezal R, Hepnarova V, Svobodova B, Kucera T, Lichnerova K, Krausova B, Horak M, Vales K, Soukup O. Kaniakova M, et al. Among authors: vales k. Biochem Pharmacol. 2021 Apr;186:114460. doi: 10.1016/j.bcp.2021.114460. Epub 2021 Feb 8. Biochem Pharmacol. 2021. PMID: 33571502
Frentizole derivatives with mTOR inhibiting and senomorphic properties.
Chrienova Z, Rysanek D, Novak J, Vasicova P, Oleksak P, Andrys R, Skarka A, Dumanovic J, Milovanovic Z, Jacevic V, Chvojkova M, Holubova K, Vales K, Skoupilova V, Valko M, Jomova K, Alomar SY, Botelho FD, Franca TCC, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: vales k. Biomed Pharmacother. 2023 Nov;167:115600. doi: 10.1016/j.biopha.2023.115600. Epub 2023 Sep 30. Biomed Pharmacother. 2023. PMID: 37783152 Free article.
7-Methoxyderivative of tacrine is a 'foot-in-the-door' open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo.
Kaniakova M, Kleteckova L, Lichnerova K, Holubova K, Skrenkova K, Korinek M, Krusek J, Smejkalova T, Korabecny J, Vales K, Soukup O, Horak M. Kaniakova M, et al. Among authors: vales k. Neuropharmacology. 2018 Sep 15;140:217-232. doi: 10.1016/j.neuropharm.2018.08.010. Epub 2018 Aug 9. Neuropharmacology. 2018. PMID: 30099049
105 results