Gao LJ - Search Results

1

3-nitropyridine analogues as novel microtubule-targeting agents.

Herman J, Vanstreels E, Bardiot D, Prota AE, Gaillard N, Gao LJ, Vercruysse T, Persoons L, Daems T, Waer M, Herdewijn P, Louat T, Steinmetz MO, De Jonghe S, Sprangers B, Daelemans D. Herman J, et al. Among authors: gao lj. PLoS One. 2024 Nov 7;19(11):e0307153. doi: 10.1371/journal.pone.0307153. eCollection 2024. PLoS One. 2024. PMID: 39509402 Free PMC article.

2

Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.

Jang MY, Lin Y, De Jonghe S, Gao LJ, Vanderhoydonck B, Froeyen M, Rozenski J, Herman J, Louat T, Van Belle K, Waer M, Herdewijn P. Jang MY, et al. Among authors: gao lj. J Med Chem. 2011 Jan 27;54(2):655-68. doi: 10.1021/jm101254z. Epub 2010 Dec 20. J Med Chem. 2011. PMID: 21171614

3

L-Aspartic and l-glutamic acid ester-based ProTides of anticancer nucleosides: Synthesis and antitumoral evaluation.

Gao LJ, De Jonghe S, Daelemans D, Herdewijn P. Gao LJ, et al. Bioorg Med Chem Lett. 2016 May 1;26(9):2142-6. doi: 10.1016/j.bmcl.2016.03.076. Epub 2016 Mar 22. Bioorg Med Chem Lett. 2016. PMID: 27032331

4

Synthesis of mizoribine prodrugs and their in vivo evaluation as immunosuppressive agents.

Gao LJ, Lin Y, De Jonghe S, Waer M, Herdewijn P. Gao LJ, et al. Bioorg Med Chem Lett. 2023 Oct 15;95:129490. doi: 10.1016/j.bmcl.2023.129490. Epub 2023 Sep 27. Bioorg Med Chem Lett. 2023. PMID: 37770001

5

Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents.

De Jonghe S, Marchand A, Gao LJ, Calleja A, Cuveliers E, Sienaert I, Herman J, Clydesdale G, Sefrioui H, Lin Y, Pfleiderer W, Waer M, Herdewijn P. De Jonghe S, et al. Among authors: gao lj. Bioorg Med Chem Lett. 2011 Jan 1;21(1):145-9. doi: 10.1016/j.bmcl.2010.11.053. Epub 2010 Nov 16. Bioorg Med Chem Lett. 2011. PMID: 21131199 Free article.

6

Synthesis and evaluation of novel ligands for the histamine H₄ receptor based on a pyrrolo[2,3-d]pyrimidine scaffold.

Gao LJ, Schwed JS, Weizel L, De Jonghe S, Stark H, Herdewijn P. Gao LJ, et al. Bioorg Med Chem Lett. 2013 Jan 1;23(1):132-7. doi: 10.1016/j.bmcl.2012.10.139. Epub 2012 Nov 15. Bioorg Med Chem Lett. 2013. PMID: 23218604

7

Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2.

Leonczak P, Gao LJ, Ramadori AT, Lescrinier E, Rozenski J, De Jonghe S, Herdewijn P. Leonczak P, et al. Among authors: gao lj. ChemMedChem. 2014 Nov;9(11):2587-601. doi: 10.1002/cmdc.201402234. Epub 2014 Aug 21. ChemMedChem. 2014. PMID: 25146684

8

Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach.

Gao LJ, Kovackova S, Sála M, Ramadori AT, De Jonghe S, Herdewijn P. Gao LJ, et al. J Med Chem. 2014 Sep 25;57(18):7624-43. doi: 10.1021/jm5007929. Epub 2014 Sep 11. J Med Chem. 2014. PMID: 25178155

9

Bifunctional aryloxyphosphoramidate prodrugs of 2'-C-Me-uridine: synthesis and anti-HCV activity.

Maiti M, Gao LJ, Huang C, Ptak RG, Murray MG, De Jonghe S, Herdewijn P. Maiti M, et al. Among authors: gao lj. Org Biomol Chem. 2016 Sep 21;14(37):8743-8757. doi: 10.1039/c6ob01189f. Org Biomol Chem. 2016. PMID: 27714209 Free PMC article.

10

Synthesis of a Nucleobase-Modified ProTide Library.

Gao LJ, Jonghe S, Herdewijn P. Gao LJ, et al. Org Lett. 2016 Nov 18;18(22):5816-5819. doi: 10.1021/acs.orglett.6b02764. Epub 2016 Oct 28. Org Lett. 2016. PMID: 27791384

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