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194 results

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Page 1
3-nitropyridine analogues as novel microtubule-targeting agents.
Herman J, Vanstreels E, Bardiot D, Prota AE, Gaillard N, Gao LJ, Vercruysse T, Persoons L, Daems T, Waer M, Herdewijn P, Louat T, Steinmetz MO, De Jonghe S, Sprangers B, Daelemans D. Herman J, et al. Among authors: steinmetz mo. PLoS One. 2024 Nov 7;19(11):e0307153. doi: 10.1371/journal.pone.0307153. eCollection 2024. PLoS One. 2024. PMID: 39509402 Free PMC article.
A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol.
Reynders M, Garścia M, Müller-Deku A, Wranik M, Krauskopf K, de la Osa de la Rosa L, Schaffer K, Jötten A, Rode A, Stierle V, Kraus Y, Baumgartner B, Ali A, Bubeneck A, Seal T, Steinmetz MO, Paulitschke P, Thorn-Seshold O. Reynders M, et al. Among authors: steinmetz mo. Chem Sci. 2024 Jul 2;15(31):12301-12309. doi: 10.1039/d4sc03072a. eCollection 2024 Aug 7. Chem Sci. 2024. PMID: 39118608 Free PMC article.
Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Homer JA, Koelln RA, Barrow AS, Gialelis TL, Boiarska Z, Steinohrt NS, Lee EF, Yang WH, Johnson RM, Chung T, Habowski AN, Vishwakarma DS, Bhunia D, Avanzi C, Moorhouse AD, Jackson M, Tuveson DA, Lyons SK, Lukey MJ, Fairlie WD, Haider SM, Steinmetz MO, Prota AE, Moses JE. Homer JA, et al. Among authors: steinmetz mo. Chem Sci. 2024 Mar 4;15(11):3879-3892. doi: 10.1039/d3sc05729a. eCollection 2024 Mar 13. Chem Sci. 2024. PMID: 38487227 Free PMC article.
A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Wranik M, Kepa MW, Beale EV, James D, Bertrand Q, Weinert T, Furrer A, Glover H, Gashi D, Carrillo M, Kondo Y, Stipp RT, Khusainov G, Nass K, Ozerov D, Cirelli C, Johnson PJM, Dworkowski F, Beale JH, Stubbs S, Zamofing T, Schneider M, Krauskopf K, Gao L, Thorn-Seshold O, Bostedt C, Bacellar C, Steinmetz MO, Milne C, Standfuss J. Wranik M, et al. Among authors: steinmetz mo. Nat Commun. 2023 Dec 2;14(1):7956. doi: 10.1038/s41467-023-43523-5. Nat Commun. 2023. PMID: 38042952 Free PMC article.
Structural insight into the stabilization of microtubules by taxanes.
Prota AE, Lucena-Agell D, Ma Y, Estevez-Gallego J, Li S, Bargsten K, Josa-Prado F, Altmann KH, Gaillard N, Kamimura S, Mühlethaler T, Gago F, Oliva MA, Steinmetz MO, Fang WS, Díaz JF. Prota AE, et al. Among authors: steinmetz mo. Elife. 2023 Mar 6;12:e84791. doi: 10.7554/eLife.84791. Elife. 2023. PMID: 36876916 Free PMC article.
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Wranik M, Weinert T, Slavov C, Masini T, Furrer A, Gaillard N, Gioia D, Ferrarotti M, James D, Glover H, Carrillo M, Kekilli D, Stipp R, Skopintsev P, Brünle S, Mühlethaler T, Beale J, Gashi D, Nass K, Ozerov D, Johnson PJM, Cirelli C, Bacellar C, Braun M, Wang M, Dworkowski F, Milne C, Cavalli A, Wachtveitl J, Steinmetz MO, Standfuss J. Wranik M, et al. Among authors: steinmetz mo. Nat Commun. 2023 Feb 17;14(1):903. doi: 10.1038/s41467-023-36481-5. Nat Commun. 2023. PMID: 36807348 Free PMC article.
194 results