Zhang W - Search Results

1

Design, synthesis and biological evaluation of novel TMPRSS2-PROTACs with florosubstituted 4-guanidino-N-phenylbenzamide derivative ligands.

Yang H, Xu H, Lin X, Cai Z, Xia Y, Wang Y, Chen Z, Zhang K, Wu Y, Wang J, Awadasseid A, Zhang W. Yang H, et al. Among authors: zhang w, zhang k. Bioorg Med Chem. 2024 Dec 15;116:117982. doi: 10.1016/j.bmc.2024.117982. Epub 2024 Oct 31. Bioorg Med Chem. 2024. PMID: 39515209

2

Design, synthesis, anti-tumor activity and mechanism of novel PROTACs as degraders of PD-L1 and inhibitors of PD-1/PD-L1 interaction.

Zhang F, Yu Q, Wu C, Sun S, Wang Y, Wang R, Chen Z, Zhang H, Xiong X, Awadasseid A, Rao G, Zhao X, Zhang W. Zhang F, et al. Among authors: zhang w, zhang h. Bioorg Med Chem. 2024 Sep 1;111:117867. doi: 10.1016/j.bmc.2024.117867. Epub 2024 Aug 3. Bioorg Med Chem. 2024. PMID: 39121678

3

Design, synthesis and biological evaluation of 2-methyl-(1,1'-biphenyl)-pyrimidine conjugates.

Chen A, Wu DL, Shi J, Narva S, Zhao XY, Wu YL, Zhang W. Chen A, et al. Among authors: zhang w. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127328. doi: 10.1016/j.bmcl.2020.127328. Epub 2020 Jun 10. Bioorg Med Chem Lett. 2020. PMID: 32631533

4

New Advances in Canonical Wnt/β-Catenin Signaling in Cancer.

Wen X, Wu Y, Awadasseid A, Tanaka Y, Zhang W. Wen X, et al. Among authors: zhang w. Cancer Manag Res. 2020 Aug 6;12:6987-6998. doi: 10.2147/CMAR.S258645. eCollection 2020. Cancer Manag Res. 2020. PMID: 32821165 Free PMC article. Review.

5

Design, synthesis and anti-cancer activity of pyrrole-imidazole polyamides through target-downregulation of c-kit gene expression.

Zhang M, Liang J, Jiang SK, Xu L, Wu YL, Awadasseid A, Zhao XY, Xiong XQ, Sugiyama H, Zhang W. Zhang M, et al. Among authors: zhang w. Eur J Med Chem. 2020 Dec 1;207:112704. doi: 10.1016/j.ejmech.2020.112704. Epub 2020 Aug 5. Eur J Med Chem. 2020. PMID: 32866755

6

Effect of 4,5-diazafluorene derivative on γδ T cell-mediated cytotoxicity against renal cell carcinoma.

Wen X, Wu Y, Tanaka Y, Awadasseid A, Tao H, Zhang W. Wen X, et al. Among authors: zhang w. Life Sci. 2021 Mar 15;269:119066. doi: 10.1016/j.lfs.2021.119066. Epub 2021 Jan 16. Life Sci. 2021. PMID: 33460663

7

Advance investigation on synthetic small-molecule inhibitors targeting PD-1/PD-L1 signaling pathway.

Awadasseid A, Wu Y, Zhang W. Awadasseid A, et al. Among authors: zhang w. Life Sci. 2021 Oct 1;282:119813. doi: 10.1016/j.lfs.2021.119813. Epub 2021 Jul 10. Life Sci. 2021. PMID: 34256042 Review.

8

Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex.

Huang Q, Wang X, Chen A, Zhang H, Yu Q, Shen C, Awadasseid A, Zhao X, Xiong X, Wu Y, Zhang W. Huang Q, et al. Among authors: zhang w, zhang h. Biochem Pharmacol. 2022 Jul;201:115062. doi: 10.1016/j.bcp.2022.115062. Epub 2022 Apr 30. Biochem Pharmacol. 2022. PMID: 35504316

9

Design, synthesis and bioactivity of novel naphthalimide-benzotriazole conjugates against A549 cells via targeting BCL2 G-quadruplex and inducing autophagy.

Wang X, Zhang M, Xiong XQ, Yang H, Wang P, Zhang K, Awadasseid A, Narva S, Wu YL, Zhang W. Wang X, et al. Among authors: zhang m, zhang w, zhang k. Life Sci. 2022 Aug 1;302:120651. doi: 10.1016/j.lfs.2022.120651. Epub 2022 May 18. Life Sci. 2022. PMID: 35597548

10

Current studies and future promises of PD-1 signal inhibitors in cervical cancer therapy.

Awadasseid A, Zhou Y, Zhang K, Tian K, Wu Y, Zhang W. Awadasseid A, et al. Among authors: zhang w, zhang k. Biomed Pharmacother. 2023 Jan;157:114057. doi: 10.1016/j.biopha.2022.114057. Epub 2022 Dec 1. Biomed Pharmacother. 2023. PMID: 36463828 Free article. Review.

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