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CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity.
Liu C, Shen M, Liu Y, Manhas A, Zhao SR, Zhang M, Belbachir N, Ren L, Zhang JZ, Caudal A, Nishiga M, Thomas D, Zhang A, Yang H, Zhou Y, Ameen M, Sayed N, Rhee JW, Qi LS, Wu JC. Liu C, et al. Among authors: yang h. Cell Stem Cell. 2024 Dec 5;31(12):1760-1776.e9. doi: 10.1016/j.stem.2024.10.007. Epub 2024 Nov 7. Cell Stem Cell. 2024. PMID: 39515331
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling.
Abilez OJ, Tzatzalos E, Yang H, Zhao MT, Jung G, Zöllner AM, Tiburcy M, Riegler J, Matsa E, Shukla P, Zhuge Y, Chour T, Chen VC, Burridge PW, Karakikes I, Kuhl E, Bernstein D, Couture LA, Gold JD, Zimmermann WH, Wu JC. Abilez OJ, et al. Among authors: yang h. Stem Cells. 2018 Feb;36(2):265-277. doi: 10.1002/stem.2732. Epub 2017 Nov 13. Stem Cells. 2018. PMID: 29086457 Free PMC article.
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs.
Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, Mitalipov S, Snyder MP, Wu JC. Zhao MT, et al. Among authors: yang h. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11111-E11120. doi: 10.1073/pnas.1708991114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203658 Free PMC article.
Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction.
Zhao X, Chen H, Xiao D, Yang H, Itzhaki I, Qin X, Chour T, Aguirre A, Lehmann K, Kim Y, Shukla P, Holmström A, Zhang JZ, Zhuge Y, Ndoye BC, Zhao M, Neofytou E, Zimmermann WH, Jain M, Wu JC. Zhao X, et al. Among authors: yang h. Stem Cell Reports. 2018 Feb 13;10(2):422-435. doi: 10.1016/j.stemcr.2018.01.002. Epub 2018 Feb 1. Stem Cell Reports. 2018. PMID: 29398480 Free PMC article.
A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.
Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, Ashley EA, Yang F, Karakikes I, Wu JC. Seeger T, et al. Among authors: yang f, yang h. Circulation. 2019 Feb 5;139(6):799-811. doi: 10.1161/CIRCULATIONAHA.118.034624. Circulation. 2019. PMID: 30586709 Free PMC article.
An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium.
Yang H, Qin X, Wang H, Zhao X, Liu Y, Wo HT, Liu C, Nishiga M, Chen H, Ge J, Sayed N, Abilez OJ, Ding D, Heilshorn SC, Li K. Yang H, et al. ACS Nano. 2019 Sep 24;13(9):9880-9894. doi: 10.1021/acsnano.9b03343. Epub 2019 Jun 7. ACS Nano. 2019. PMID: 31149806 Free PMC article.
Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates.
Wilson KD, Ameen M, Guo H, Abilez OJ, Tian L, Mumbach MR, Diecke S, Qin X, Liu Y, Yang H, Ma N, Gaddam S, Cunningham NJ, Gu M, Neofytou E, Prado M, Hildebrandt TB, Karakikes I, Chang HY, Wu JC. Wilson KD, et al. Among authors: yang h. Dev Cell. 2020 Sep 28;54(6):694-709.e9. doi: 10.1016/j.devcel.2020.07.006. Epub 2020 Aug 6. Dev Cell. 2020. PMID: 32763147 Free PMC article.
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