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Page 1
GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis.
He X, Hawkins C, Lawley L, Phan TM, Park I, Joven N, Zhang J, Wunderlich M, Mizukawa B, Pei S, Patel A, VanOudenhove J, Halene S, Fang J. He X, et al. Among authors: mizukawa b. Biochim Biophys Acta Mol Basis Dis. 2025 Jan;1871(1):167565. doi: 10.1016/j.bbadis.2024.167565. Epub 2024 Nov 8. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39522891 Free article.
SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation.
Chang YH, Yamamoto K, Fujino T, Wang TW, Sugimoto E, Zhang W, Yabushita T, Suzaki K, Pietsch EC, Weir BA, Crescenzo R, Cowley GS, Attar R, Philippar U, Wunderlich M, Mizukawa B, Zheng Y, Enomoto Y, Imai Y, Kitamura T, Goyama S. Chang YH, et al. Among authors: mizukawa b. Cell Rep. 2024 Aug 27;43(8):114536. doi: 10.1016/j.celrep.2024.114536. Epub 2024 Aug 2. Cell Rep. 2024. PMID: 39096901 Free article.
Clinical outcomes of hypomethylating agents and venetoclax in newly diagnosed unfit and relapsed/refractory paediatric, adolescent and young adult acute myeloid leukaemia patients.
LeBlanc FR, Breese EH, Burns KC, Chang EK, Jones LM, Lee L, Mizukawa B, Norris RE, O'Brien MM, Phillips CL, Perentesis JP, Rubinstein J, Pommert L. LeBlanc FR, et al. Among authors: mizukawa b. Br J Haematol. 2024 Sep;205(3):1055-1066. doi: 10.1111/bjh.19679. Epub 2024 Jul 31. Br J Haematol. 2024. PMID: 39082439
The Choice of Either Conventional Chemotherapy or Inotuzumab Ozogamicin as Bridging Regimen Does Not Appear To Impact Clinical Response to CD19-Directed CAR-T Therapy in Pediatric B-ALL.
Rubinstein JD, Breese EH, Krupski MC, O'Brien MM, Dandoy CE, Mizukawa B, Khoury R, Norris RE, Davies SM, Phillips CL. Rubinstein JD, et al. Among authors: mizukawa b. Transplant Cell Ther. 2023 May;29(5):311.e1-311.e7. doi: 10.1016/j.jtct.2023.02.012. Epub 2023 Feb 19. Transplant Cell Ther. 2023. PMID: 36809824 Free article.
IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia.
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, Asada S, Fujino T, Fukushima T, Yonezawa T, Tanaka Y, Fukuyama T, Tsuchiya A, Shikata S, Iwamura H, Kinouchi C, Komatsu K, Yamasaki S, Shibata T, Sasaki AT, Schibler J, Wunderlich M, O'Brien E, Mizukawa B, Mulloy JC, Sugiura Y, Takizawa H, Shibata T, Miyake K, Kitamura T, Goyama S. Liu X, et al. Among authors: mizukawa b. EMBO Mol Med. 2023 Jan 11;15(1):e15631. doi: 10.15252/emmm.202115631. Epub 2022 Dec 1. EMBO Mol Med. 2023. PMID: 36453131 Free PMC article.
Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia.
Hegde S, Gasilina A, Wunderlich M, Lin Y, Buchholzer M, Krumbach OHF, Akbarzadeh M, Ahmadian MR, Seibel W, Zheng Y, Perentesis JP, Mizukawa BE, Vinnedge LP, Cancelas JA, Nassar NN. Hegde S, et al. Among authors: mizukawa be. Leukemia. 2022 Mar;36(3):637-647. doi: 10.1038/s41375-021-01455-3. Epub 2021 Oct 28. Leukemia. 2022. PMID: 34711926 Free PMC article.
Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms.
Sabnis HS, Shulman DS, Mizukawa B, Bouvier N, Zehir A, Fangusaro J, Fabrizio VA, Whitlow C, Winchester M, Agresta L, Turpin B, Wechsler DS, DuBois SG, Glade-Bender J, Castellino SM, Shukla N. Sabnis HS, et al. Among authors: mizukawa b. J Clin Oncol. 2021 Dec 1;39(34):3822-3828. doi: 10.1200/JCO.21.01213. Epub 2021 Sep 30. J Clin Oncol. 2021. PMID: 34591650 Free PMC article.
Treatment of posttransplant lymphoproliferative disorder with poor prognostic features in children and young adults: Short-course EPOCH regimens are safe and effective.
Rubinstein JD, Shah R, Breese EH, Burns KC, Mangino JL, Norris RE, Lee L, Mizukawa B, O'Brien MM, Phillips CL, Perentesis JP, Pommert L, Absalon MJ. Rubinstein JD, et al. Among authors: mizukawa b. Pediatr Blood Cancer. 2021 Aug;68(8):e29126. doi: 10.1002/pbc.29126. Epub 2021 May 21. Pediatr Blood Cancer. 2021. PMID: 34019326
31 results