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14,875 results

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GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis.
He X, Hawkins C, Lawley L, Phan TM, Park I, Joven N, Zhang J, Wunderlich M, Mizukawa B, Pei S, Patel A, VanOudenhove J, Halene S, Fang J. He X, et al. Among authors: patel a. Biochim Biophys Acta Mol Basis Dis. 2025 Jan;1871(1):167565. doi: 10.1016/j.bbadis.2024.167565. Epub 2024 Nov 8. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39522891 Free article.
Cyclosporine enhances the sensitivity to lenalidomide in MDS/AML in vitro.
He X, Dou A, Feng S, Roman-Rivera A, Hawkins C, Lawley L, Zhang J, Wunderlich M, Mizukawa B, Halene S, Patel A, Fang J. He X, et al. Among authors: patel a. Exp Hematol. 2020 Jun;86:21-27.e2. doi: 10.1016/j.exphem.2020.05.001. Epub 2020 May 8. Exp Hematol. 2020. PMID: 32437909 Free PMC article.
In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2.
Gbyli R, Song Y, Liu W, Gao Y, Biancon G, Chandhok NS, Wang X, Fu X, Patel A, Sundaram R, Tebaldi T, Mamillapalli P, Zeidan AM, Flavell RA, Prebet T, Bindra RS, Halene S. Gbyli R, et al. Among authors: patel a. Leukemia. 2022 May;36(5):1313-1323. doi: 10.1038/s41375-022-01536-x. Epub 2022 Mar 10. Leukemia. 2022. PMID: 35273342 Free PMC article.
ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control.
Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S. Gao Y, et al. Among authors: patel a. Cell Rep. 2023 Oct 31;42(10):113163. doi: 10.1016/j.celrep.2023.113163. Epub 2023 Sep 23. Cell Rep. 2023. PMID: 37742191 Free PMC article.
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.
Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA. Song Y, et al. Among authors: patel a. Science. 2021 Mar 5;371(6533):1019-1025. doi: 10.1126/science.abe2485. Science. 2021. PMID: 33674488 Free PMC article.
Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, Courchaine E, Barentine AES, Machyna M, Botti V, Qin A, Gbyli R, Patel A, Song Y, Kiefer L, Viero G, Neuenkirchen N, Lin H, Bewersdorf J, Simon MD, Neugebauer KM, Tebaldi T, Halene S. Biancon G, et al. Among authors: patel a. Mol Cell. 2022 Mar 17;82(6):1107-1122.e7. doi: 10.1016/j.molcel.2022.02.025. Mol Cell. 2022. PMID: 35303483 Free PMC article.
Circulating markers of angiogenesis and endotheliopathy in COVID-19.
Pine AB, Meizlish ML, Goshua G, Chang CH, Zhang H, Bishai J, Bahel P, Patel A, Gbyli R, Kwan JM, Won CH, Price C, Dela Cruz CS, Halene S, van Dijk D, Hwa J, Lee AI, Chun HJ. Pine AB, et al. Among authors: patel a. Pulm Circ. 2020 Nov 25;10(4):2045894020966547. doi: 10.1177/2045894020966547. eCollection 2020 Oct-Dec. Pulm Circ. 2020. PMID: 33282193 Free PMC article.
Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.
Meizlish ML, Pine AB, Goshua G, Chang CH, Zhang H, Bishai J, Bahel P, Patel A, Gbyli R, Kwan J, Price C, Cruz CSD, Halene S, van Dijk D, Hwa J, Lee AI, Chun HJ. Meizlish ML, et al. Among authors: patel a. medRxiv [Preprint]. 2020 Jul 1:2020.06.29.20140376. doi: 10.1101/2020.06.29.20140376. medRxiv. 2020. Update in: Pulm Circ. 2020 Nov 25;10(4):2045894020966547. doi: 10.1177/2045894020966547 PMID: 32637968 Free PMC article. Updated. Preprint.
A Phase 2 Randomized, Double-Blind, Placebo-controlled Trial of Oral Camostat Mesylate for Early Treatment of COVID-19 Outpatients Showed Shorter Illness Course and Attenuation of Loss of Smell and Taste.
Chupp G, Spichler-Moffarah A, Søgaard OS, Esserman D, Dziura J, Danzig L, Chaurasia R, Patra KP, Salovey A, Nunez A, May J, Astorino L, Patel A, Halene S, Wang J, Hui P, Patel P, Lu J, Li F, Gan G, Parziale S, Katsovich L, Desir GV, Vinetz JM. Chupp G, et al. Among authors: patel p, patel a. medRxiv [Preprint]. 2022 Jan 31:2022.01.28.22270035. doi: 10.1101/2022.01.28.22270035. medRxiv. 2022. PMID: 35132421 Free PMC article. Preprint.
A neutrophil activation signature predicts critical illness and mortality in COVID-19.
Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. Meizlish ML, et al. Among authors: patel a. Blood Adv. 2021 Mar 9;5(5):1164-1177. doi: 10.1182/bloodadvances.2020003568. Blood Adv. 2021. PMID: 33635335 Free PMC article.
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