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Spermine oxidase promotes Helicobacter pylori-mediated gastric carcinogenesis through acrolein production.
McNamara KM, Sierra JC, Latour YL, Hawkins CV, Asim M, Williams KJ, Barry DP, Allaman MM, Zagol-Ikapitte I, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Tyree RN, Carson KS, Choksi YA, Coburn LA, Gobert AP, Wilson KT. McNamara KM, et al. Among authors: schneider c. Oncogene. 2024 Nov 10. doi: 10.1038/s41388-024-03218-7. Online ahead of print. Oncogene. 2024. PMID: 39523394
α-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY.
Sierra JC, Suarez G, Piazuelo MB, Luis PB, Baker DR, Romero-Gallo J, Barry DP, Schneider C, Morgan DR, Peek RM Jr, Gobert AP, Wilson KT. Sierra JC, et al. Among authors: schneider c. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5077-5085. doi: 10.1073/pnas.1814497116. Epub 2019 Feb 25. Proc Natl Acad Sci U S A. 2019. PMID: 30804204 Free PMC article.
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Sierra JC, Piazuelo MB, Luis PB, Barry DP, Allaman MM, Asim M, Sebrell TA, Finley JL, Rose KL, Hill S, Holshouser SL, Casero RA, Cleveland JL, Woster PM, Schey KL, Bimczok D, Schneider C, Gobert AP, Wilson KT. Sierra JC, et al. Among authors: schneider c. Oncogene. 2020 May;39(22):4465-4474. doi: 10.1038/s41388-020-1304-6. Epub 2020 Apr 29. Oncogene. 2020. PMID: 32350444 Free PMC article.
Ornithine Decarboxylase in Gastric Epithelial Cells Promotes the Immunopathogenesis of Helicobacter pylori Infection.
Latour YL, Sierra JC, McNamara KM, Smith TM, Luis PB, Schneider C, Delgado AG, Barry DP, Allaman MM, Calcutt MW, Schey KL, Piazuelo MB, Gobert AP, Wilson KT. Latour YL, et al. Among authors: schneider c. J Immunol. 2022 Aug 15;209(4):796-805. doi: 10.4049/jimmunol.2100795. Epub 2022 Jul 27. J Immunol. 2022. PMID: 35896340 Free PMC article.
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Hardbower DM, Asim M, Luis PB, Singh K, Barry DP, Yang C, Steeves MA, Cleveland JL, Schneider C, Piazuelo MB, Gobert AP, Wilson KT. Hardbower DM, et al. Among authors: schneider c. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E751-E760. doi: 10.1073/pnas.1614958114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096401 Free PMC article.
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Singh K, Coburn LA, Asim M, Barry DP, Allaman MM, Shi C, Washington MK, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Cleveland JL, Gobert AP, Wilson KT. Singh K, et al. Among authors: schneider c. Cancer Res. 2018 Aug 1;78(15):4303-4315. doi: 10.1158/0008-5472.CAN-18-0116. Epub 2018 May 31. Cancer Res. 2018. PMID: 29853605 Free PMC article.
Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection.
Gobert AP, Al-Greene NT, Singh K, Coburn LA, Sierra JC, Verriere TG, Luis PB, Schneider C, Asim M, Allaman MM, Barry DP, Cleveland JL, Destefano Shields CE, Casero RA Jr, Washington MK, Piazuelo MB, Wilson KT. Gobert AP, et al. Among authors: schneider c. Front Immunol. 2018 Jun 5;9:1242. doi: 10.3389/fimmu.2018.01242. eCollection 2018. Front Immunol. 2018. PMID: 29922289 Free PMC article.
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Gobert AP, Latour YL, Asim M, Barry DP, Allaman MM, Finley JL, Smith TM, McNamara KM, Singh K, Sierra JC, Delgado AG, Luis PB, Schneider C, Washington MK, Piazuelo MB, Zhao S, Coburn LA, Wilson KT. Gobert AP, et al. Among authors: schneider c. Gastroenterology. 2022 Mar;162(3):813-827.e8. doi: 10.1053/j.gastro.2021.11.005. Epub 2021 Nov 10. Gastroenterology. 2022. PMID: 34767785 Free PMC article.
Curcumin Oxidation Is Required for Inhibition of Helicobacter pylori Growth, Translocation and Phosphorylation of Cag A.
Ray AK, Luis PB, Mishra SK, Barry DP, Asim M, Pandey A, Chaturvedi M, Gupta J, Gupta S, Mahant S, Das R, Kumar P, Shalimar, Wilson KT, Schneider C, Chaturvedi R. Ray AK, et al. Among authors: schneider c. Front Cell Infect Microbiol. 2021 Dec 24;11:765842. doi: 10.3389/fcimb.2021.765842. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 35004346 Free PMC article.
3,700 results