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Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region.
Chen J, Zhang H, Fu T, Zhao J, Nowak JK, Kalla R, Wellens J, Yuan S, Noble A, Ventham NT, Dunlop MG, Halfvarson J, Mao R, Theodoratou E, Satsangi J, Li X. Chen J, et al. Among authors: li x. EBioMedicine. 2024 Dec;110:105443. doi: 10.1016/j.ebiom.2024.105443. Epub 2024 Nov 13. EBioMedicine. 2024. PMID: 39536393 Free PMC article.
Finally, our findings were validated through genome-wide DNA methylation analysis of UC, as well as co-localization and gene expression analyses. FINDINGS: Higher exposures to NO(x) (HR = 1.20, 95% CI 1.05-1.38), NO(2) (HR = 1.19, 95% CI = 1.03-1.36), PM(2.5) (HR = 1.19, 9 …
Finally, our findings were validated through genome-wide DNA methylation analysis of UC, as well as co-localization and gene expression anal …
Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae.
Yuan S, Li Y, Wang L, Xu F, Chen J, Levin MG, Xiong Y, Voight BF, Damrauer SM, Gill D, Burgess S, Åkesson A, Michaëlsson K, Li X, Shen X, Larsson SC. Yuan S, et al. Among authors: li y, li x. medRxiv [Preprint]. 2023 Jul 25:2023.07.20.23292938. doi: 10.1101/2023.07.20.23292938. medRxiv. 2023. PMID: 37546828 Free PMC article. Preprint.
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