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Large- and Small-Animal Studies of Safety, Pharmacokinetics, and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs.
Risen S, Sharma S, Gilberto VS, Brindley S, Aguilar M, Brown JM, Chatterjee A, Moreno JA, Nagpal P. Risen S, et al. Among authors: gilberto vs. ACS Pharmacol Transl Sci. 2024 Mar 21;7(11):3439-3451. doi: 10.1021/acsptsci.4c00068. eCollection 2024 Nov 8. ACS Pharmacol Transl Sci. 2024. PMID: 39539269
Targeting Neuroinflammation by Pharmacologic Downregulation of Inflammatory Pathways Is Neuroprotective in Protein Misfolding Disorders.
Risen SJ, Boland SW, Sharma S, Weisman GM, Shirley PM, Latham AS, Hay AJD, Gilberto VS, Hines AD, Brindley S, Brown JM, McGrath S, Chatterjee A, Nagpal P, Moreno JA. Risen SJ, et al. Among authors: gilberto vs. ACS Chem Neurosci. 2024 Apr 3;15(7):1533-1547. doi: 10.1021/acschemneuro.3c00846. Epub 2024 Mar 20. ACS Chem Neurosci. 2024. PMID: 38507813
Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy.
Wahl D, Risen SJ, Osburn SC, Emge T, Sharma S, Gilberto VS, Chatterjee A, Nagpal P, Moreno JA, LaRocca TJ. Wahl D, et al. Among authors: gilberto vs. bioRxiv [Preprint]. 2024 Jun 4:2024.02.03.578493. doi: 10.1101/2024.02.03.578493. bioRxiv. 2024. Update in: J Neuroinflammation. 2024 Jul 27;21(1):182. doi: 10.1186/s12974-024-03182-9 PMID: 38370618 Free PMC article. Updated. Preprint.