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6,034 results

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Engineered receptors for soluble cellular communication and disease sensing.
Piraner DI, Abedi MH, Duran Gonzalez MJ, Chazin-Gray A, Lin A, Zhu I, Ravindran PT, Schlichthaerle T, Huang B, Bearchild TH, Lee D, Wyman S, Jun YW, Baker D, Roybal KT. Piraner DI, et al. Among authors: lin a. Nature. 2024 Nov 14. doi: 10.1038/s41586-024-08366-0. Online ahead of print. Nature. 2024. PMID: 39542025
Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.
Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, Jun YW. Kwak M, et al. Among authors: lin a. Nat Cell Biol. 2022 Dec;24(12):1739-1753. doi: 10.1038/s41556-022-01031-6. Epub 2022 Dec 1. Nat Cell Biol. 2022. PMID: 36456828 Free PMC article.
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.
Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR. Gaschler MM, et al. Among authors: lin aj. Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. Epub 2018 Apr 2. Nat Chem Biol. 2018. PMID: 29610484 Free PMC article.
Small-molecule allosteric inhibitors of GPX4.
Liu H, Forouhar F, Lin AJ, Wang Q, Polychronidou V, Soni RK, Xia X, Stockwell BR. Liu H, et al. Cell Chem Biol. 2022 Dec 15;29(12):1680-1693.e9. doi: 10.1016/j.chembiol.2022.11.003. Epub 2022 Nov 23. Cell Chem Biol. 2022. PMID: 36423641 Free PMC article.
Comprehensive discovery and functional characterization of the noncanonical proteome.
Shi C, Liu F, Su X, Yang Z, Wang Y, Xie S, Xie S, Sun Q, Chen Y, Sang L, Tan M, Zhu L, Lei K, Li J, Yang J, Gao Z, Yu M, Wang X, Wang J, Chen J, Zhuo W, Fang Z, Liu J, Yan Q, Neculai D, Sun Q, Shao J, Lin W, Liu W, Chen J, Wang L, Liu Y, Li X, Zhou T, Lin A. Shi C, et al. Among authors: lin a. Cell Res. 2025 Jan 10. doi: 10.1038/s41422-024-01059-3. Online ahead of print. Cell Res. 2025. PMID: 39794466
Water, sanitation, handwashing, and nutritional interventions can reduce child antibiotic use: evidence from Bangladesh and Kenya.
Ercumen A, Mertens AN, Butzin-Dozier Z, Jung DK, Ali S, Achando BS, Rao G, Hemlock C, Pickering AJ, Stewart CP, Tan ST, Grembi JA, Benjamin-Chung J, Wolfe M, Ho GG, Rahman MZ, Arnold CD, Dentz HN, Njenga SM, Meerkerk T, Chen B, Nadimpalli M, Islam MA, Hubbard AE, Null C, Unicomb L, Rahman M, Colford JM Jr, Luby SP, Arnold BF, Lin A. Ercumen A, et al. Among authors: lin a. Nat Commun. 2025 Jan 9;16(1):556. doi: 10.1038/s41467-024-55801-x. Nat Commun. 2025. PMID: 39788996 Free PMC article. Clinical Trial.
6,034 results