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973 results

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Page 1
Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores.
Abramowitz SA, Boulier K, Keat K, Cardone KM, Shivakumar M, DePaolo J, Judy R, Bermudez F, Mimouni N, Neylan C, Kim D, Rader DJ, Ritchie MD, Voight BF, Pasaniuc B, Levin MG, Damrauer SM; Penn Medicine BioBank. Abramowitz SA, et al. Among authors: rader dj. JAMA. 2025 Jan 7;333(1):60-70. doi: 10.1001/jama.2024.23784. JAMA. 2025. PMID: 39549270
Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity.
Gouma S, Weirick ME, Bolton MJ, Arevalo CP, Goodwin EC, Anderson EM, McAllister CM, Christensen SR, Dunbar D, Fiore D, Brock A, Weaver J, Millar J, DerOhannessian S; UPenn COVID Processing Unit; Frank I, Rader DJ, Wherry EJ, Hensley SE. Gouma S, et al. Among authors: rader dj. medRxiv [Preprint]. 2021 Apr 19:2021.04.12.21255324. doi: 10.1101/2021.04.12.21255324. medRxiv. 2021. Update in: JCI Insight. 2021 Aug 23;6(16):150449. doi: 10.1172/jci.insight.150449 PMID: 33907765 Free PMC article. Updated. Preprint.
Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.
Zhang C, Verma A, Feng Y, Melo MCR, McQuillan M, Hansen M, Lucas A, Park J, Ranciaro A, Thompson S, Rubel MA, Campbell MC, Beggs W, Hirbo J, Mpoloka SW, Mokone GG; Regeneron Genetic Center; Nyambo T, Meskel DW, Belay G, Fokunang C, Njamnshi AK, Omar SA, Williams SM, Rader D, Ritchie MD, de la Fuente Nunez C, Sirugo G, Tishkoff S. Zhang C, et al. medRxiv [Preprint]. 2021 Aug 7:2021.06.28.21259529. doi: 10.1101/2021.06.28.21259529. medRxiv. 2021. Update in: Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2123000119. doi: 10.1073/pnas.2123000119 PMID: 34230933 Free PMC article. Updated. Preprint.
Comparison of the structure-function properties of wild-type human apoA-V and a C-terminal truncation associated with elevated plasma triglycerides.
Stankov S, Vitali C, Park J, Nguyen D, Mayne L, Englander SW; Regeneron Genetics Center; Levin MG, Vujkovic M, Hand NJ, Phillips MC, Rader DJ. Stankov S, et al. Among authors: rader dj. medRxiv [Preprint]. 2023 Feb 23:2023.02.21.23286268. doi: 10.1101/2023.02.21.23286268. medRxiv. 2023. PMID: 36865344 Free PMC article. Preprint.
Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.
Lee DSM, Cardone KM, Zhang DY, Tsao NL, Abramowitz S, Sharma P, DePaolo JS, Conery M, Aragam KG, Biddinger K, Dilitikas O, Hoffman-Andrews L, Judy RL, Khan A, Kulo I, Puckelwartz MJ, Reza N, Satterfield BA, Singhal P; Regeneron Genetics Center; Arany ZP, Cappola TP, Carruth E, Day SM, Do R, Haggarty CM, Joseph J, McNally EM, Nadkarni G, Owens AT, Rader DJ, Ritchie MD, Sun YV, Voight BF, Levin MG, Damrauer SM. Lee DSM, et al. Among authors: rader dj. medRxiv [Preprint]. 2024 Oct 23:2023.07.16.23292724. doi: 10.1101/2023.07.16.23292724. medRxiv. 2024. PMID: 37503172 Free PMC article. Preprint.
Clinical correlates of CT imaging-derived phenotypes among lean and overweight patients with hepatic steatosis.
Song I, Thompson EW, Verma A, MacLean MT, Duda J, Elahi A, Tran R, Raghupathy P, Swago S, Hazim M, Bhattaru A, Schneider C, Vujkovic M, Torigian DA, Kahn CE, Gee JC, Borthakur A, Kripke CM, Carson CC, Carr R, Jehangir Q, Ko YA, Litt H, Rosen M, Mankoff DA, Schnall MD, Shou H, Chirinos J, Damrauer SM, Serper M, Chen J, Rader DJ; Penn Medicine BioBank; Witschey WRT, Sagreiya H. Song I, et al. Among authors: rader dj. Sci Rep. 2024 Jan 2;14(1):53. doi: 10.1038/s41598-023-49470-x. Sci Rep. 2024. PMID: 38167550 Free PMC article.
A deep catalogue of protein-coding variation in 983,578 individuals.
Sun KY, Bai X, Chen S, Bao S, Zhang C, Kapoor M, Backman J, Joseph T, Maxwell E, Mitra G, Gorovits A, Mansfield A, Boutkov B, Gokhale S, Habegger L, Marcketta A, Locke AE, Ganel L, Hawes A, Kessler MD, Sharma D, Staples J, Bovijn J, Gelfman S, Di Gioia A, Rajagopal VM, Lopez A, Varela JR, Alegre-Díaz J, Berumen J, Tapia-Conyer R, Kuri-Morales P, Torres J, Emberson J, Collins R; Regeneron Genetics Center; RGC-ME Cohort Partners; Cantor M, Thornton T, Kang HM, Overton JD, Shuldiner AR, Cremona ML, Nafde M, Baras A, Abecasis G, Marchini J, Reid JG, Salerno W, Balasubramanian S. Sun KY, et al. Nature. 2024 Jul;631(8021):583-592. doi: 10.1038/s41586-024-07556-0. Epub 2024 May 20. Nature. 2024. PMID: 38768635 Free PMC article.
CT imaging-derived phenotypes for abdominal muscle and their association with age and sex in a medical biobank.
Vu PT, Chahine C, Chatterjee N, MacLean MT, Swago S, Bhattaru A, Thompson EW, Ikhlas A, Oteng E, Davidson L, Tran R, Hazim M, Raghupathy P, Verma A, Duda J, Gee J, Luks V, Gershuni V, Wu G, Rader D, Sagreiya H, Witschey WR; Penn Medicine Biobank. Vu PT, et al. Sci Rep. 2024 Jun 26;14(1):14807. doi: 10.1038/s41598-024-64603-6. Sci Rep. 2024. PMID: 38926479 Free PMC article.
973 results