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An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
Kyriazi D, Voth L, Bader A, Ewert W, Gerlach J, Elfrink K, Franz P, Tsap MI, Schirmer B, Damiano-Guercio J, Hartmann FK, Plenge M, Salari A, Schöttelndreier D, Strienke K, Bresch N, Salinas C, Gutzeit HO, Schaumann N, Hussein K, Bähre H, Brüsch I, Claus P, Neumann D, Taft MH, Shcherbata HR, Ngezahayo A, Bähler M, Amiri M, Knölker HJ, Preller M, Tsiavaliaris G. Kyriazi D, et al. Among authors: claus p. Nat Commun. 2024 Nov 16;15(1):9947. doi: 10.1038/s41467-024-54181-6. Nat Commun. 2024. PMID: 39550360 Free PMC article.
The spinal muscular atrophy gene product regulates actin dynamics.
Schüning T, Zeug A, Strienke K, Franz P, Tsiavaliaris G, Hensel N, Viero G, Ponimaskin E, Claus P. Schüning T, et al. Among authors: claus p. FASEB J. 2024 Sep 30;38(18):e70055. doi: 10.1096/fj.202300183R. FASEB J. 2024. PMID: 39305126
The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.
Nölle A, Zeug A, van Bergeijk J, Tönges L, Gerhard R, Brinkmann H, Al Rayes S, Hensel N, Schill Y, Apkhazava D, Jablonka S, O'mer J, Srivastav RK, Baasner A, Lingor P, Wirth B, Ponimaskin E, Niedenthal R, Grothe C, Claus P. Nölle A, et al. Among authors: claus p. Hum Mol Genet. 2011 Dec 15;20(24):4865-78. doi: 10.1093/hmg/ddr425. Epub 2011 Sep 14. Hum Mol Genet. 2011. PMID: 21920940
Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle.
Schada von Borzyskowski L, Severi F, Krüger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Cortina NS, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ. Schada von Borzyskowski L, et al. Among authors: claus p. Nature. 2019 Nov;575(7783):500-504. doi: 10.1038/s41586-019-1748-4. Epub 2019 Nov 13. Nature. 2019. PMID: 31723261
Vitamin D improves endothelial barrier integrity and counteracts inflammatory effects on endothelial progenitor cells.
Schröder-Heurich B, von Hardenberg S, Brodowski L, Kipke B, Meyer N, Borns K, von Kaisenberg CS, Brinkmann H, Claus P, von Versen-Höynck F. Schröder-Heurich B, et al. Among authors: claus p. FASEB J. 2019 Aug;33(8):9142-9153. doi: 10.1096/fj.201802750RR. Epub 2019 May 14. FASEB J. 2019. PMID: 31084577
-Schroder-Heurich, B., von Hardenberg, S., Brodowski, L., Kipke, B., Meyer, N., Borns, K., von Kaisenberg, C. S., Brinkmann, H., Claus, P., von Versen-Hoynck, F. Vitamin D improves endothelial barrier integrity and counteracts inflammatory effects on endothelial pro …
-Schroder-Heurich, B., von Hardenberg, S., Brodowski, L., Kipke, B., Meyer, N., Borns, K., von Kaisenberg, C. S., Brinkmann, H., Claus
Profilin2 regulates actin rod assembly in neuronal cells.
Walter LM, Rademacher S, Pich A, Claus P. Walter LM, et al. Among authors: claus p. Sci Rep. 2021 May 13;11(1):10287. doi: 10.1038/s41598-021-89397-9. Sci Rep. 2021. PMID: 33986363 Free PMC article.
382 results