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4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells.
Eldehna WM, Fares M, Bonardi A, Avgenikos M, Baselious F, Schmidt M, Al-Warhi T, Abdel-Aziz HA, Rennert R, Peat TS, Supuran CT, Wessjohann LA, Ibrahim HS. Eldehna WM, et al. Among authors: avgenikos m. J Med Chem. 2024 Nov 28;67(22):20438-20454. doi: 10.1021/acs.jmedchem.4c01894. Epub 2024 Nov 17. J Med Chem. 2024. PMID: 39550697 Free PMC article.
A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice.
Sabarwal A, van Rooyen JC, Caburet J, Avgenikos M, Dheeraj A, Ali M, Mishra D, de Meester JSB, Stander S, van Otterlo WAL, Kaschula CH, Singh RP. Sabarwal A, et al. Among authors: avgenikos m. FASEB J. 2022 Dec;36(12):e22654. doi: 10.1096/fj.202200669RR. FASEB J. 2022. PMID: 36421014
Novel indole sulfides as potent HIV-1 NNRTIs.
Brigg S, Pribut N, Basson AE, Avgenikos M, Venter R, Blackie MA, van Otterlo WAL, Pelly SC. Brigg S, et al. Among authors: avgenikos m. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1580-1584. doi: 10.1016/j.bmcl.2016.02.006. Epub 2016 Feb 4. Bioorg Med Chem Lett. 2016. PMID: 26876929