Hu J - Search Results

1

Role of Mitochondrial Iron Uptake in Acetaminophen Hepatotoxicity.

Hu J, Nieminen AL, Zhong Z, Lemasters JJ. Hu J, et al. Livers. 2024 Sep;4(3):333-351. doi: 10.3390/livers4030024. Epub 2024 Jul 30. Livers. 2024. PMID: 39554796 Free PMC article.

2

Suppression of iron mobilization from lysosomes to mitochondria attenuates liver injury after acetaminophen overdose in vivo in mice: Protection by minocycline.

Hu J, Lemasters JJ. Hu J, et al. Toxicol Appl Pharmacol. 2020 Apr 1;392:114930. doi: 10.1016/j.taap.2020.114930. Epub 2020 Feb 25. Toxicol Appl Pharmacol. 2020. PMID: 32109512 Free PMC article.

3

Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization.

Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Wimborne HJ, et al. Among authors: hu j. Toxicol Appl Pharmacol. 2020 Jun 1;396:114982. doi: 10.1016/j.taap.2020.114982. Epub 2020 Mar 30. Toxicol Appl Pharmacol. 2020. PMID: 32240663 Free PMC article.

4

The mitochondrial calcium uniporter mediates mitochondrial Fe²⁺ uptake and hepatotoxicity after acetaminophen.

Hu J, Nieminen AL, Weemhoff JL, Jaeschke H, Murphy LG, Dent JA, Lemasters JJ. Hu J, et al. Toxicol Appl Pharmacol. 2023 Nov 15;479:116722. doi: 10.1016/j.taap.2023.116722. Epub 2023 Oct 15. Toxicol Appl Pharmacol. 2023. PMID: 37848124 Free PMC article.

5

Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver.

Hu J, Ramshesh VK, McGill MR, Jaeschke H, Lemasters JJ. Hu J, et al. Toxicol Sci. 2016 Mar;150(1):204-15. doi: 10.1093/toxsci/kfv319. Epub 2015 Dec 31. Toxicol Sci. 2016. PMID: 26721299 Free PMC article.

6

Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline.

Hu J, Kholmukhamedov A, Lindsey CC, Beeson CC, Jaeschke H, Lemasters JJ. Hu J, et al. Free Radic Biol Med. 2016 Aug;97:418-426. doi: 10.1016/j.freeradbiomed.2016.06.024. Epub 2016 Jun 23. Free Radic Biol Med. 2016. PMID: 27345134 Free PMC article.

7

A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria.

Kholmukhamedov A, Li L, Lindsey CC, Hu J, Nieminen AL, Takemoto K, Beeson GC, Beneker CM, McInnes C, Beeson CC, Lemasters JJ. Kholmukhamedov A, et al. Among authors: hu j. J Biol Chem. 2022 Sep;298(9):102336. doi: 10.1016/j.jbc.2022.102336. Epub 2022 Aug 2. J Biol Chem. 2022. PMID: 35931111 Free PMC article.

8

MitoTracker Red for isolation of zone-specific hepatocytes and characterization of hepatic sublobular metabolism.

Savoca M, Takemoto K, Hu J, Li L, Jacob Kendrick B, Zhong Z, Lemasters JJ. Savoca M, et al. Among authors: hu j. Biochem Biophys Res Commun. 2024 Nov 26;735:150457. doi: 10.1016/j.bbrc.2024.150457. Epub 2024 Jul 26. Biochem Biophys Res Commun. 2024. PMID: 39146811

9

Cyclosporin A in left ventricular remodeling after myocardial infarction.

Kholmukhamedov A, Logdon C, Hu J, McKinney RA, Spinale FG, Lemasters JJ, Mukherjee R. Kholmukhamedov A, et al. Among authors: hu j. Am J Physiol Heart Circ Physiol. 2014 Jan 1;306(1):H53-9. doi: 10.1152/ajpheart.00079.2013. Epub 2013 Oct 25. Am J Physiol Heart Circ Physiol. 2014. PMID: 24163074 Free PMC article.

10

Minocycline and doxycycline, but not tetracycline, mitigate liver and kidney injury after hemorrhagic shock/resuscitation.

Kholmukhamedov A, Czerny C, Hu J, Schwartz J, Zhong Z, Lemasters JJ. Kholmukhamedov A, et al. Among authors: hu j. Shock. 2014 Sep;42(3):256-63. doi: 10.1097/SHK.0000000000000213. Shock. 2014. PMID: 24978888 Free PMC article.

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