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Elotuzumab-mediated ADCC with Th1-like Vγ9Vδ2 T cells to disrupt myeloma-osteoclast interaction.
Inoue Y, Tenshin H, Teramachi J, Sumitani R, Oda A, Maeda Y, Oura M, Sogabe K, Maruhashi T, Takahashi M, Fujii S, Nakamura S, Miki H, Hara T, Endo I, Kagawa K, Ozaki S, Hiasa M, Harada T, Abe M. Inoue Y, et al. Among authors: maruhashi t. Cancer Sci. 2024 Nov 18. doi: 10.1111/cas.16401. Online ahead of print. Cancer Sci. 2024. PMID: 39557586 Free article.
TGF-β-activated kinase-1 inhibitor LL-Z1640-2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF-α and RANKL expression.
Tenshin H, Teramachi J, Ashtar M, Hiasa M, Inoue Y, Oda A, Tanimoto K, Shimizu S, Higa Y, Harada T, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Sebe M, Tsutsumi R, Sakaue H, Endo I, Matsumoto T, Tanaka E, Abe M. Tenshin H, et al. Among authors: maruhashi t. Clin Transl Immunology. 2022 Jan 19;11(1):e1371. doi: 10.1002/cti2.1371. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35079379 Free PMC article.
Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase.
Harada T, Ohguchi H, Oda A, Nakao M, Teramachi J, Hiasa M, Sumitani R, Oura M, Sogabe K, Maruhashi T, Takahashi M, Fujii S, Nakamura S, Miki H, Kagawa K, Ozaki S, Sano S, Hideshima T, Abe M. Harada T, et al. Among authors: maruhashi t. Blood Adv. 2023 Mar 28;7(6):1019-1032. doi: 10.1182/bloodadvances.2022007155. Blood Adv. 2023. PMID: 36129197 Free PMC article.
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2.
Higa Y, Hiasa M, Tenshin H, Nakaue E, Tanaka M, Kim S, Nakagawa M, Shimizu S, Tanimoto K, Teramachi J, Harada T, Oda A, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Matsumoto T, Tanaka E, Abe M. Higa Y, et al. Among authors: maruhashi t. Antioxidants (Basel). 2023 Jan 5;12(1):133. doi: 10.3390/antiox12010133. Antioxidants (Basel). 2023. PMID: 36670994 Free PMC article.
Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors.
Nakaue E, Teramachi J, Tenshin H, Hiasa M, Harada T, Oda A, Inoue Y, Shimizu S, Higa Y, Sogabe K, Oura M, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Tanaka E, Abe M. Nakaue E, et al. Among authors: maruhashi t. Int J Hematol. 2023 Jul;118(1):88-98. doi: 10.1007/s12185-023-03601-2. Epub 2023 Apr 11. Int J Hematol. 2023. PMID: 37039914 Free PMC article.
Therapeutic efficacy of the resorcylic acid lactone LL-Z1640-2 for adult T-cell leukaemia/lymphoma.
Oura M, Harada T, Oda A, Teramachi J, Nakayama A, Sumitani R, Inoue Y, Maeda Y, Sogabe K, Maruhashi T, Takahashi M, Fujii S, Nakamura S, Miki H, Nakamura M, Hara T, Yamagami H, Kurahashi K, Endo I, Hasegawa H, Fujiwara H, Abe M. Oura M, et al. Among authors: maruhashi t. EJHaem. 2023 Jul 27;4(3):667-678. doi: 10.1002/jha2.758. eCollection 2023 Aug. EJHaem. 2023. PMID: 37601887 Free PMC article.
Acute accumulation of PIM2 and NRF2 and recovery of β5 subunit activity mitigate multiple myeloma cell susceptibility to proteasome inhibitors.
Sogabe K, Nakamura S, Higa Y, Miki H, Oda A, Maruhashi T, Sumitani R, Oura M, Takahashi M, Nakamura M, Maeda Y, Hara T, Yamagami H, Fujii S, Kagawa K, Ozaki S, Kurahashi K, Endo I, Aihara KI, Nakaue E, Hiasa M, Teramachi J, Harada T, Abe M. Sogabe K, et al. Among authors: maruhashi t. Int J Hematol. 2024 Mar;119(3):303-315. doi: 10.1007/s12185-023-03705-9. Epub 2024 Jan 21. Int J Hematol. 2024. PMID: 38245883
291 results